Tong Z - Search Results

1

Metabolism of intravenous methylnaltrexone in mice, rats, dogs, and humans.

Chandrasekaran A, Tong Z, Li H, Erve JC, DeMaio W, Goljer I, McConnell O, Rotshteyn Y, Hultin T, Talaat R, Scatina J. Chandrasekaran A, et al. Among authors: tong z. Drug Metab Dispos. 2010 Apr;38(4):606-16. doi: 10.1124/dmd.109.031179. Epub 2010 Jan 6. Drug Metab Dispos. 2010. PMID: 20053817 Clinical Trial.

2

In vitro glucuronidation of thyroxine and triiodothyronine by liver microsomes and recombinant human UDP-glucuronosyltransferases.

Tong Z, Li H, Goljer I, McConnell O, Chandrasekaran A. Tong Z, et al. Drug Metab Dispos. 2007 Dec;35(12):2203-10. doi: 10.1124/dmd.107.016972. Epub 2007 Sep 17. Drug Metab Dispos. 2007. PMID: 17875670

3

Species differences in the formation of vabicaserin carbamoyl glucuronide.

Tong Z, Chandrasekaran A, DeMaio W, Jordan R, Li H, Moore R, Poola N, Burghart P, Hultin T, Scatina J. Tong Z, et al. Drug Metab Dispos. 2010 Apr;38(4):581-90. doi: 10.1124/dmd.109.028639. Epub 2009 Dec 23. Drug Metab Dispos. 2010. PMID: 20032194 Clinical Trial.

4

In vitro metabolism and identification of human enzymes involved in the metabolism of methylnaltrexone.

Tong Z, Chandrasekaran A, Li H, Rotshteyn Y, Erve JC, Demaio W, Talaat R, Hultin T, Scatina J. Tong Z, et al. Drug Metab Dispos. 2010 May;38(5):801-7. doi: 10.1124/dmd.110.032169. Epub 2010 Feb 19. Drug Metab Dispos. 2010. PMID: 20173089

5

Metabolism of vabicaserin in mice, rats, dogs, monkeys, and humans.

Tong Z, Chandrasekaran A, DeMaio W, Espina R, Lu W, Jordan R, Scatina J. Tong Z, et al. Drug Metab Dispos. 2010 Dec;38(12):2266-77. doi: 10.1124/dmd.110.033670. Epub 2010 Aug 25. Drug Metab Dispos. 2010. PMID: 20739639

6

Nuclear magnetic resonance spectroscopy as a quantitative tool to determine the concentrations of biologically produced metabolites: implications in metabolites in safety testing.

Espina R, Yu L, Wang J, Tong Z, Vashishtha S, Talaat R, Scatina J, Mutlib A. Espina R, et al. Among authors: tong z. Chem Res Toxicol. 2009 Feb;22(2):299-310. doi: 10.1021/tx800251p. Chem Res Toxicol. 2009. PMID: 18980340

7

Effects of ertiprotafib on hepatic cytochrome P450 and peroxisomal enzymes in rats and dogs, and in rat and human primary hepatocytes.

Tong Z, Chandrasekaran A, Jordan R, Markiewicz V, Li H, Xiang Q, Shen L, Scatina J. Tong Z, et al. Xenobiotica. 2007 Jan;37(1):1-18. doi: 10.1080/00498250600965115. Xenobiotica. 2007. PMID: 17178630

8

Mechanistic toxicogenomic analysis of WAY-144122 administration in Sprague-Dawley rats.

Peterson RL, Casciotti L, Block L, Goad ME, Tong Z, Meehan JT, Jordan RA, Vinlove MP, Markiewicz VR, Weed CA, Dorner AJ. Peterson RL, et al. Among authors: tong z. Toxicol Appl Pharmacol. 2004 Apr 1;196(1):80-94. doi: 10.1016/j.taap.2003.11.016. Toxicol Appl Pharmacol. 2004. PMID: 15050410

9

"Cocktail" approaches and strategies in drug development: valuable tool or flawed science?

Zhou H, Tong Z, McLeod JF. Zhou H, et al. Among authors: tong z. J Clin Pharmacol. 2004 Feb;44(2):120-34. doi: 10.1177/0091270003261333. J Clin Pharmacol. 2004. PMID: 14747420 Review.

10

A Modified Ligature-Induced Peri-Implantitis Murine Model and RNA Sequencing Analysis Compared With Human Subjects.

Tong ZA, Chen L, Shen L, Lu YF, Zhang JW, Qi YD, Qian YJ, Bao SQ, Chen W, Si MS. Tong ZA, et al. J Clin Periodontol. 2025 Jan 16. doi: 10.1111/jcpe.14127. Online ahead of print. J Clin Periodontol. 2025. PMID: 39821935

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