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NCX 4040, a nitric oxide-donating aspirin, exerts anti-inflammatory effects through inhibition of I kappa B-alpha degradation in human monocytes.
Ricciotti E, Dovizio M, Di Francesco L, Anzellotti P, Salvatore T, Di Francesco A, Sciulli MG, Pistritto G, Monopoli A, Patrignani P. Ricciotti E, et al. Among authors: di francesco a, di francesco l. J Immunol. 2010 Feb 15;184(4):2140-7. doi: 10.4049/jimmunol.0903107. Epub 2010 Jan 11. J Immunol. 2010. PMID: 20065114
Effects of AF3442 [N-(9-ethyl-9H-carbazol-3-yl)-2-(trifluoromethyl)benzamide], a novel inhibitor of human microsomal prostaglandin E synthase-1, on prostanoid biosynthesis in human monocytes in vitro.
Bruno A, Di Francesco L, Coletta I, Mangano G, Alisi MA, Polenzani L, Milanese C, Anzellotti P, Ricciotti E, Dovizio M, Di Francesco A, Tacconelli S, Capone ML, Patrignani P. Bruno A, et al. Among authors: di francesco a, di francesco l. Biochem Pharmacol. 2010 Apr 1;79(7):974-81. doi: 10.1016/j.bcp.2009.11.011. Epub 2009 Nov 27. Biochem Pharmacol. 2010. PMID: 19925781
De novo synthesis of cyclooxygenase-1 counteracts the suppression of platelet thromboxane biosynthesis by aspirin.
Evangelista V, Manarini S, Di Santo A, Capone ML, Ricciotti E, Di Francesco L, Tacconelli S, Sacchetti A, D'Angelo S, Scilimati A, Sciulli MG, Patrignani P. Evangelista V, et al. Among authors: di francesco l, di santo a. Circ Res. 2006 Mar 17;98(5):593-5. doi: 10.1161/01.RES.0000214553.37930.3e. Epub 2006 Feb 16. Circ Res. 2006. PMID: 16484611
Pharmacodynamic of cyclooxygenase inhibitors in humans.
Capone ML, Tacconelli S, Di Francesco L, Sacchetti A, Sciulli MG, Patrignani P. Capone ML, et al. Among authors: di francesco l. Prostaglandins Other Lipid Mediat. 2007 Jan;82(1-4):85-94. doi: 10.1016/j.prostaglandins.2006.05.019. Epub 2006 Jul 3. Prostaglandins Other Lipid Mediat. 2007. PMID: 17164136 Review.
Human pharmacology of naproxen sodium.
Capone ML, Tacconelli S, Sciulli MG, Anzellotti P, Di Francesco L, Merciaro G, Di Gregorio P, Patrignani P. Capone ML, et al. Among authors: di gregorio p, di francesco l. J Pharmacol Exp Ther. 2007 Aug;322(2):453-60. doi: 10.1124/jpet.107.122283. Epub 2007 May 1. J Pharmacol Exp Ther. 2007. PMID: 17473175 Clinical Trial.
Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells.
Di Francesco L, Totani L, Dovizio M, Piccoli A, Di Francesco A, Salvatore T, Pandolfi A, Evangelista V, Dercho RA, Seta F, Patrignani P. Di Francesco L, et al. Among authors: di francesco a. Circ Res. 2009 Feb 27;104(4):506-13. doi: 10.1161/CIRCRESAHA.108.191114. Epub 2009 Jan 2. Circ Res. 2009. PMID: 19122175
Low-dose naproxen interferes with the antiplatelet effects of aspirin in healthy subjects: recommendations to minimize the functional consequences.
Anzellotti P, Capone ML, Jeyam A, Tacconelli S, Bruno A, Tontodonati P, Di Francesco L, Grossi L, Renda G, Merciaro G, Di Gregorio P, Price TS, Garcia Rodriguez LA, Patrignani P. Anzellotti P, et al. Among authors: di gregorio p, di francesco l. Arthritis Rheum. 2011 Mar;63(3):850-9. doi: 10.1002/art.30175. Arthritis Rheum. 2011. PMID: 21360514 Free article. Clinical Trial.
Effects of celecoxib on prostanoid biosynthesis and circulating angiogenesis proteins in familial adenomatous polyposis.
Dovizio M, Tacconelli S, Ricciotti E, Bruno A, Maier TJ, Anzellotti P, Di Francesco L, Sala P, Signoroni S, Bertario L, Dixon DA, Lawson JA, Steinhilber D, FitzGerald GA, Patrignani P. Dovizio M, et al. Among authors: di francesco l. J Pharmacol Exp Ther. 2012 Apr;341(1):242-50. doi: 10.1124/jpet.111.190785. Epub 2012 Jan 19. J Pharmacol Exp Ther. 2012. PMID: 22262921 Free PMC article.
Pharmacological inhibition of platelet-tumor cell cross-talk prevents platelet-induced overexpression of cyclooxygenase-2 in HT29 human colon carcinoma cells.
Dovizio M, Maier TJ, Alberti S, Di Francesco L, Marcantoni E, Münch G, John CM, Suess B, Sgambato A, Steinhilber D, Patrignani P. Dovizio M, et al. Among authors: di francesco l. Mol Pharmacol. 2013 Jul;84(1):25-40. doi: 10.1124/mol.113.084988. Epub 2013 Apr 11. Mol Pharmacol. 2013. PMID: 23580446 Free PMC article.
222 results