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BMP-7 blocks mesenchymal conversion of mesothelial cells and prevents peritoneal damage induced by dialysis fluid exposure.
Loureiro J, Schilte M, Aguilera A, Albar-Vizcaíno P, Ramírez-Huesca M, Pérez-Lozano ML, González-Mateo G, Aroeira LS, Selgas R, Mendoza L, Ortiz A, Ruíz-Ortega M, van den Born J, Beelen RH, López-Cabrera M. Loureiro J, et al. Nephrol Dial Transplant. 2010 Apr;25(4):1098-108. doi: 10.1093/ndt/gfp618. Epub 2010 Jan 12. Nephrol Dial Transplant. 2010. PMID: 20067910
PPAR-γ agonist rosiglitazone protects peritoneal membrane from dialysis fluid-induced damage.
Sandoval P, Loureiro J, González-Mateo G, Pérez-Lozano ML, Maldonado-Rodríguez A, Sánchez-Tomero JA, Mendoza L, Santamaría B, Ortiz A, Ruíz-Ortega M, Selgas R, Martín P, Sánchez-Madrid F, Aguilera A, López-Cabrera M. Sandoval P, et al. Lab Invest. 2010 Oct;90(10):1517-32. doi: 10.1038/labinvest.2010.111. Epub 2010 Jun 7. Lab Invest. 2010. PMID: 20531289 Free article.
Low-GDP peritoneal dialysis fluid ('balance') has less impact in vitro and ex vivo on epithelial-to-mesenchymal transition (EMT) of mesothelial cells than a standard fluid.
Bajo MA, Pérez-Lozano ML, Albar-Vizcaino P, del Peso G, Castro MJ, Gonzalez-Mateo G, Fernández-Perpén A, Aguilera A, Sánchez-Villanueva R, Sánchez-Tomero JA, López-Cabrera M, Peter ME, Passlick-Deetjen J, Selgas R. Bajo MA, et al. Nephrol Dial Transplant. 2011 Jan;26(1):282-91. doi: 10.1093/ndt/gfq357. Epub 2010 Jun 22. Nephrol Dial Transplant. 2011. PMID: 20571097
Blocking TGF-β1 protects the peritoneal membrane from dialysate-induced damage.
Loureiro J, Aguilera A, Selgas R, Sandoval P, Albar-Vizcaíno P, Pérez-Lozano ML, Ruiz-Carpio V, Majano PL, Lamas S, Rodríguez-Pascual F, Borras-Cuesta F, Dotor J, López-Cabrera M. Loureiro J, et al. J Am Soc Nephrol. 2011 Sep;22(9):1682-95. doi: 10.1681/ASN.2010111197. Epub 2011 Jul 8. J Am Soc Nephrol. 2011. PMID: 21742730 Free PMC article.
Influence of bicarbonate/low-GDP peritoneal dialysis fluid (BicaVera) on in vitro and ex vivo epithelial-to-mesenchymal transition of mesothelial cells.
Fernández-Perpén A, Pérez-Lozano ML, Bajo MA, Albar-Vizcaino P, Sandoval Correa P, del Peso G, Castro MJ, Aguilera A, Ossorio M, Peter ME, Passlick-Deetjen J, Aroeira LS, Selgas R, López-Cabrera M, Sánchez-Tomero JA. Fernández-Perpén A, et al. Perit Dial Int. 2012 May-Jun;32(3):292-304. doi: 10.3747/pdi.2010.00315. Epub 2012 Jan 3. Perit Dial Int. 2012. PMID: 22215656 Free PMC article.
Mesenchymal conversion of mesothelial cells as a mechanism responsible for high solute transport rate in peritoneal dialysis: role of vascular endothelial growth factor.
Aroeira LS, Aguilera A, Selgas R, Ramírez-Huesca M, Pérez-Lozano ML, Cirugeda A, Bajo MA, del Peso G, Sánchez-Tomero JA, Jiménez-Heffernan JA, López-Cabrera M. Aroeira LS, et al. Am J Kidney Dis. 2005 Nov;46(5):938-48. doi: 10.1053/j.ajkd.2005.08.011. Am J Kidney Dis. 2005. PMID: 16253736
Cyclooxygenase-2 mediates dialysate-induced alterations of the peritoneal membrane.
Aroeira LS, Lara-Pezzi E, Loureiro J, Aguilera A, Ramírez-Huesca M, González-Mateo G, Pérez-Lozano ML, Albar-Vizcaíno P, Bajo MA, del Peso G, Sánchez-Tomero JA, Jiménez-Heffernan JA, Selgas R, López-Cabrera M. Aroeira LS, et al. J Am Soc Nephrol. 2009 Mar;20(3):582-92. doi: 10.1681/ASN.2008020211. Epub 2009 Jan 21. J Am Soc Nephrol. 2009. PMID: 19158357 Free PMC article.
23 results