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Page 1
The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.
Jinwal UK, Koren J 3rd, Borysov SI, Schmid AB, Abisambra JF, Blair LJ, Johnson AG, Jones JR, Shults CL, O'Leary JC 3rd, Jin Y, Buchner J, Cox MB, Dickey CA. Jinwal UK, et al. Among authors: buchner j. J Neurosci. 2010 Jan 13;30(2):591-9. doi: 10.1523/JNEUROSCI.4815-09.2010. J Neurosci. 2010. PMID: 20071522 Free PMC article.
Substrate transfer from the chaperone Hsp70 to Hsp90.
Wegele H, Wandinger SK, Schmid AB, Reinstein J, Buchner J. Wegele H, et al. Among authors: buchner j. J Mol Biol. 2006 Feb 24;356(3):802-11. doi: 10.1016/j.jmb.2005.12.008. Epub 2005 Dec 20. J Mol Biol. 2006. PMID: 16403523
The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop.
Schmid AB, Lagleder S, Gräwert MA, Röhl A, Hagn F, Wandinger SK, Cox MB, Demmer O, Richter K, Groll M, Kessler H, Buchner J. Schmid AB, et al. Among authors: buchner j. EMBO J. 2012 Mar 21;31(6):1506-17. doi: 10.1038/emboj.2011.472. Epub 2012 Jan 6. EMBO J. 2012. PMID: 22227520 Free PMC article.
The cochaperone SGTA (small glutamine-rich tetratricopeptide repeat-containing protein alpha) demonstrates regulatory specificity for the androgen, glucocorticoid, and progesterone receptors.
Paul A, Garcia YA, Zierer B, Patwardhan C, Gutierrez O, Hildenbrand Z, Harris DC, Balsiger HA, Sivils JC, Johnson JL, Buchner J, Chadli A, Cox MB. Paul A, et al. Among authors: buchner j. J Biol Chem. 2014 May 30;289(22):15297-308. doi: 10.1074/jbc.M113.535229. Epub 2014 Apr 21. J Biol Chem. 2014. PMID: 24753260 Free PMC article.
Hop/Sti1 phosphorylation inhibits its co-chaperone function.
Röhl A, Tippel F, Bender E, Schmid AB, Richter K, Madl T, Buchner J. Röhl A, et al. Among authors: buchner j. EMBO Rep. 2015 Feb;16(2):240-9. doi: 10.15252/embr.201439198. Epub 2014 Dec 12. EMBO Rep. 2015. PMID: 25504578 Free PMC article.
Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD.
Sabbagh JJ, Cordova RA, Zheng D, Criado-Marrero M, Lemus A, Li P, Baker JD, Nordhues BA, Darling AL, Martinez-Licha C, Rutz DA, Patel S, Buchner J, Leahy JW, Koren J 3rd, Dickey CA, Blair LJ. Sabbagh JJ, et al. Among authors: buchner j. ACS Chem Biol. 2018 Aug 17;13(8):2288-2299. doi: 10.1021/acschembio.8b00454. Epub 2018 Jun 19. ACS Chem Biol. 2018. PMID: 29893552 Free PMC article.
349 results