Näthke IS - Search Results

1

Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo.

Buchert M, Athineos D, Abud HE, Burke ZD, Faux MC, Samuel MS, Jarnicki AG, Winbanks CE, Newton IP, Meniel VS, Suzuki H, Stacker SA, Näthke IS, Tosh D, Huelsken J, Clarke AR, Heath JK, Sansom OJ, Ernst M. Buchert M, et al. Among authors: nathke is. PLoS Genet. 2010 Jan 15;6(1):e1000816. doi: 10.1371/journal.pgen.1000816. PLoS Genet. 2010. PMID: 20084116 Free PMC article.

2

Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration.

Sansom OJ, Reed KR, Hayes AJ, Ireland H, Brinkmann H, Newton IP, Batlle E, Simon-Assmann P, Clevers H, Nathke IS, Clarke AR, Winton DJ. Sansom OJ, et al. Among authors: nathke is. Genes Dev. 2004 Jun 15;18(12):1385-90. doi: 10.1101/gad.287404. Genes Dev. 2004. PMID: 15198980 Free PMC article.

3

Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis.

Dikovskaya D, Schiffmann D, Newton IP, Oakley A, Kroboth K, Sansom O, Jamieson TJ, Meniel V, Clarke A, Näthke IS. Dikovskaya D, et al. Among authors: nathke is. J Cell Biol. 2007 Jan 15;176(2):183-95. doi: 10.1083/jcb.200610099. J Cell Biol. 2007. PMID: 17227893 Free PMC article.

4

Interkinetic nuclear migration and basal tethering facilitates post-mitotic daughter separation in intestinal organoids.

Carroll TD, Langlands AJ, Osborne JM, Newton IP, Appleton PL, Näthke I. Carroll TD, et al. J Cell Sci. 2017 Nov 15;130(22):3862-3877. doi: 10.1242/jcs.211656. Epub 2017 Oct 5. J Cell Sci. 2017. PMID: 28982714 Free PMC article.

5

Adenomatous polyposis coli and hypoxia-inducible factor-1{alpha} have an antagonistic connection.

Newton IP, Kenneth NS, Appleton PL, Näthke I, Rocha S. Newton IP, et al. Mol Biol Cell. 2010 Nov 1;21(21):3630-8. doi: 10.1091/mbc.E10-04-0312. Epub 2010 Sep 15. Mol Biol Cell. 2010. PMID: 20844082 Free PMC article.

6

Defining the role of APC in the mitotic spindle checkpoint in vivo: APC-deficient cells are resistant to Taxol.

Radulescu S, Ridgway RA, Appleton P, Kroboth K, Patel S, Woodgett J, Taylor S, Nathke IS, Sansom OJ. Radulescu S, et al. Among authors: nathke is. Oncogene. 2010 Dec 9;29(49):6418-27. doi: 10.1038/onc.2010.373. Epub 2010 Aug 23. Oncogene. 2010. PMID: 20729907 Free PMC article.

7

Paneth Cell-Rich Regions Separated by a Cluster of Lgr5+ Cells Initiate Crypt Fission in the Intestinal Stem Cell Niche.

Langlands AJ, Almet AA, Appleton PL, Newton IP, Osborne JM, Näthke IS. Langlands AJ, et al. Among authors: nathke is. PLoS Biol. 2016 Jun 27;14(6):e1002491. doi: 10.1371/journal.pbio.1002491. eCollection 2016 Jun. PLoS Biol. 2016. PMID: 27348469 Free PMC article.

8

Novel self-association of the APC molecule affects APC clusters and cell migration.

Li Z, Kroboth K, Newton IP, Näthke IS. Li Z, et al. Among authors: nathke is. J Cell Sci. 2008 Jun 1;121(11):1916-25. doi: 10.1242/jcs.029470. Epub 2008 May 13. J Cell Sci. 2008. PMID: 18477604 Free article.

9

Identification of Endogenous Adenomatous Polyposis Coli Interaction Partners and β-Catenin-Independent Targets by Proteomics.

Popow O, Paulo JA, Tatham MH, Volk MS, Rojas-Fernandez A, Loyer N, Newton IP, Januschke J, Haigis KM, Näthke I. Popow O, et al. Mol Cancer Res. 2019 Sep;17(9):1828-1841. doi: 10.1158/1541-7786.MCR-18-1154. Epub 2019 Jun 3. Mol Cancer Res. 2019. PMID: 31160382 Free PMC article.

10

Loss of adenomatous polyposis coli function renders intestinal epithelial cells resistant to the cytokine IL-22.

Chen Y, Vandereyken M, Newton IP, Moraga I, Näthke IS, Swamy M. Chen Y, et al. Among authors: nathke is. PLoS Biol. 2019 Nov 26;17(11):e3000540. doi: 10.1371/journal.pbio.3000540. eCollection 2019 Nov. PLoS Biol. 2019. PMID: 31770366 Free PMC article.

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