II. Synthesis and biological evaluation of some bioisosteres and congeners of the antitumor agent, 2-(4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy)propionic acid (XK469).
Hazeldine ST, Polin L, Kushner J, White K, Bouregeois NM, Crantz B, Palomino E, Corbett TH, Horwitz JP.
Hazeldine ST, et al. Among authors: kushner j.
J Med Chem. 2002 Jul 4;45(14):3130-7. doi: 10.1021/jm0200097.
J Med Chem. 2002.
PMID: 12086498
The synthetic approach to each of the bioisosteres of 1 utilized the methodology developed in previous work (see Hazeldine, S. T.; Polin, L.; Kushner, J.; Paluch, J.; White, K.; Edelstein, M.; Palomino, E.; Corbett, T. H.; Horwitz, J. ...Design, Synthe …
The synthetic approach to each of the bioisosteres of 1 utilized the methodology developed in previous work (see Hazeldine, S. T.; Polin, L. …