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Brucella abortus induces the secretion of proinflammatory mediators from glial cells leading to astrocyte apoptosis.
García Samartino C, Delpino MV, Pott Godoy C, Di Genaro MS, Pasquevich KA, Zwerdling A, Barrionuevo P, Mathieu P, Cassataro J, Pitossi F, Giambartolomei GH. García Samartino C, et al. Among authors: giambartolomei gh. Am J Pathol. 2010 Mar;176(3):1323-38. doi: 10.2353/ajpath.2010.090503. Epub 2010 Jan 21. Am J Pathol. 2010. PMID: 20093491 Free PMC article.
Brucella lumazine synthase elicits a mixed Th1-Th2 immune response and reduces infection in mice challenged with Brucella abortus 544 independently of the adjuvant formulation used.
Velikovsky CA, Goldbaum FA, Cassataro J, Estein S, Bowden RA, Bruno L, Fossati CA, Giambartolomei GH. Velikovsky CA, et al. Among authors: giambartolomei gh. Infect Immun. 2003 Oct;71(10):5750-5. doi: 10.1128/IAI.71.10.5750-5755.2003. Infect Immun. 2003. PMID: 14500496 Free PMC article.
A DNA vaccine coding for the Brucella outer membrane protein 31 confers protection against B. melitensis and B. ovis infection by eliciting a specific cytotoxic response.
Cassataro J, Velikovsky CA, de la Barrera S, Estein SM, Bruno L, Bowden R, Pasquevich KA, Fossati CA, Giambartolomei GH. Cassataro J, et al. Among authors: giambartolomei gh. Infect Immun. 2005 Oct;73(10):6537-46. doi: 10.1128/IAI.73.10.6537-6546.2005. Infect Immun. 2005. PMID: 16177328 Free PMC article.
Vaccination with the recombinant Brucella outer membrane protein 31 or a derived 27-amino-acid synthetic peptide elicits a CD4+ T helper 1 response that protects against Brucella melitensis infection.
Cassataro J, Estein SM, Pasquevich KA, Velikovsky CA, de la Barrera S, Bowden R, Fossati CA, Giambartolomei GH. Cassataro J, et al. Among authors: giambartolomei gh. Infect Immun. 2005 Dec;73(12):8079-88. doi: 10.1128/IAI.73.12.8079-8088.2005. Infect Immun. 2005. PMID: 16299302 Free PMC article.
Immunization with murine breast cancer cells treated with antisense oligodeoxynucleotides to type I insulin-like growth factor receptor induced an antitumoral effect mediated by a CD8+ response involving Fas/Fas ligand cytotoxic pathway.
Schillaci R, Salatino M, Cassataro J, Proietti CJ, Giambartolomei GH, Rivas MA, Carnevale RP, Charreau EH, Elizalde PV. Schillaci R, et al. Among authors: giambartolomei gh. J Immunol. 2006 Mar 15;176(6):3426-37. doi: 10.4049/jimmunol.176.6.3426. J Immunol. 2006. PMID: 16517711
Improved immunogenicity of a vaccination regimen combining a DNA vaccine encoding Brucella melitensis outer membrane protein 31 (Omp31) and recombinant Omp31 boosting.
Cassataro J, Velikovsky CA, Bruno L, Estein SM, de la Barrera S, Bowden R, Fossati CA, Giambartolomei GH. Cassataro J, et al. Among authors: giambartolomei gh. Clin Vaccine Immunol. 2007 Jul;14(7):869-74. doi: 10.1128/CVI.00472-06. Epub 2007 Apr 11. Clin Vaccine Immunol. 2007. PMID: 17428946 Free PMC article.
97 results