Broaddus RR - Search Results

1

Constitutive activation of smoothened leads to female infertility and altered uterine differentiation in the mouse.

Franco HL, Lee KY, Rubel CA, Creighton CJ, White LD, Broaddus RR, Lewis MT, Lydon JP, Jeong JW, DeMayo FJ. Franco HL, et al. Among authors: broaddus rr. Biol Reprod. 2010 May;82(5):991-9. doi: 10.1095/biolreprod.109.081513. Epub 2010 Feb 3. Biol Reprod. 2010. PMID: 20130264 Free PMC article.

2

Generation of a Mig-6 conditional null allele.

Jin N, Gilbert JL, Broaddus RR, Demayo FJ, Jeong JW. Jin N, et al. Among authors: broaddus rr. Genesis. 2007 Nov;45(11):716-21. doi: 10.1002/dvg.20348. Genesis. 2007. PMID: 17987665

3

beta-catenin mediates glandular formation and dysregulation of beta-catenin induces hyperplasia formation in the murine uterus.

Jeong JW, Lee HS, Franco HL, Broaddus RR, Taketo MM, Tsai SY, Lydon JP, DeMayo FJ. Jeong JW, et al. Among authors: broaddus rr. Oncogene. 2009 Jan 8;28(1):31-40. doi: 10.1038/onc.2008.363. Epub 2008 Sep 22. Oncogene. 2009. PMID: 18806829 Free PMC article.

4

Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease.

Jeong JW, Lee HS, Lee KY, White LD, Broaddus RR, Zhang YW, Vande Woude GF, Giudice LC, Young SL, Lessey BA, Tsai SY, Lydon JP, DeMayo FJ. Jeong JW, et al. Among authors: broaddus rr. Proc Natl Acad Sci U S A. 2009 May 26;106(21):8677-82. doi: 10.1073/pnas.0903632106. Epub 2009 May 13. Proc Natl Acad Sci U S A. 2009. PMID: 19439667 Free PMC article.

5

The Synergistic Effect of Conditional Pten Loss and Oncogenic K-ras Mutation on Endometrial Cancer Development Occurs via Decreased Progesterone Receptor Action.

Kim TH, Wang J, Lee KY, Franco HL, Broaddus RR, Lydon JP, Jeong JW, Demayo FJ. Kim TH, et al. Among authors: broaddus rr. J Oncol. 2010;2010:139087. doi: 10.1155/2010/139087. Epub 2009 Oct 27. J Oncol. 2010. PMID: 19884980 Free PMC article.

6

Ablation of Indian hedgehog in the murine uterus results in decreased cell cycle progression, aberrant epidermal growth factor signaling, and increased estrogen signaling.

Franco HL, Lee KY, Broaddus RR, White LD, Lanske B, Lydon JP, Jeong JW, DeMayo FJ. Franco HL, et al. Among authors: broaddus rr. Biol Reprod. 2010 Apr;82(4):783-90. doi: 10.1095/biolreprod.109.080259. Epub 2010 Jan 7. Biol Reprod. 2010. PMID: 20056671 Free PMC article.

7

The synergistic effect of Mig-6 and Pten ablation on endometrial cancer development and progression.

Kim TH, Franco HL, Jung SY, Qin J, Broaddus RR, Lydon JP, Jeong JW. Kim TH, et al. Among authors: broaddus rr. Oncogene. 2010 Jul 1;29(26):3770-80. doi: 10.1038/onc.2010.126. Epub 2010 Apr 26. Oncogene. 2010. PMID: 20418913 Free PMC article.

8

β-Catenin activation contributes to the pathogenesis of adenomyosis through epithelial-mesenchymal transition.

Oh SJ, Shin JH, Kim TH, Lee HS, Yoo JY, Ahn JY, Broaddus RR, Taketo MM, Lydon JP, Leach RE, Lessey BA, Fazleabas AT, Lim JM, Jeong JW. Oh SJ, et al. Among authors: broaddus rr. J Pathol. 2013 Oct;231(2):210-22. doi: 10.1002/path.4224. J Pathol. 2013. PMID: 23784889 Free PMC article.

9

Critical tumor suppressor function mediated by epithelial Mig-6 in endometrial cancer.

Kim TH, Lee DK, Cho SN, Orvis GD, Behringer RR, Lydon JP, Ku BJ, McCampbell AS, Broaddus RR, Jeong JW. Kim TH, et al. Among authors: broaddus rr. Cancer Res. 2013 Aug 15;73(16):5090-9. doi: 10.1158/0008-5472.CAN-13-0241. Epub 2013 Jun 27. Cancer Res. 2013. PMID: 23811943 Free PMC article.

10

Mig-6 suppresses endometrial cancer associated with Pten deficiency and ERK activation.

Kim TH, Yoo JY, Kim HI, Gilbert J, Ku BJ, Li J, Mills GB, Broaddus RR, Lydon JP, Lim JM, Yoon HG, Jeong JW. Kim TH, et al. Among authors: broaddus rr. Cancer Res. 2014 Dec 15;74(24):7371-82. doi: 10.1158/0008-5472.CAN-14-0794. Epub 2014 Nov 6. Cancer Res. 2014. PMID: 25377472 Free PMC article.

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