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Exploratory drug safety: a discovery strategy to reduce attrition in development.
Bass AS, Cartwright ME, Mahon C, Morrison R, Snyder R, McNamara P, Bradley P, Zhou YY, Hunter J. Bass AS, et al. Among authors: cartwright me. J Pharmacol Toxicol Methods. 2009 Jul-Aug;60(1):69-78. doi: 10.1016/j.vascn.2009.04.194. Epub 2009 May 5. J Pharmacol Toxicol Methods. 2009. PMID: 19422924 Review.
alpha2-adrenoceptor agonists as nasal decongestants.
Corboz MR, Mutter JC, Rivelli MA, Mingo GG, McLeod RL, Varty L, Jia Y, Cartwright M, Hey JA. Corboz MR, et al. Pulm Pharmacol Ther. 2007;20(2):149-56. doi: 10.1016/j.pupt.2006.03.012. Epub 2006 May 6. Pulm Pharmacol Ther. 2007. PMID: 16809058
Discovery of liver-targeted inhibitors of stearoyl-CoA desaturase (SCD1).
Deng Y, Yang Z, Shipps GW Jr, Lo SM, West R, Hwa J, Zheng S, Farley C, Lachowicz J, van Heek M, Bass AS, Sinha DP, Mahon CR, Cartwright ME. Deng Y, et al. Among authors: cartwright me. Bioorg Med Chem Lett. 2013 Feb 1;23(3):791-6. doi: 10.1016/j.bmcl.2012.11.075. Epub 2012 Dec 5. Bioorg Med Chem Lett. 2013. PMID: 23265904
Discovery of MK-8831, A Novel Spiro-Proline Macrocycle as a Pan-Genotypic HCV-NS3/4a Protease Inhibitor.
Neelamkavil SF, Agrawal S, Bara T, Bennett C, Bhat S, Biswas D, Brockunier L, Buist N, Burnette D, Cartwright M, Chackalamannil S, Chase R, Chelliah M, Chen A, Clasby M, Colandrea VJ, Davies IW, Eagen K, Guo Z, Han Y, Howe J, Jayne C, Josien H, Kargman S, Marcantonio K, Miao S, Miller R, Nolting A, Pinto P, Rajagopalan M, Ruck RT, Shah U, Soriano A, Sperbeck D, Velazquez F, Wu J, Xia Y, Venkatraman S. Neelamkavil SF, et al. ACS Med Chem Lett. 2015 Dec 22;7(1):111-6. doi: 10.1021/acsmedchemlett.5b00425. eCollection 2016 Jan 14. ACS Med Chem Lett. 2015. PMID: 26819676 Free PMC article.
34 results