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Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties.
Billerbeck E, Kang YH, Walker L, Lockstone H, Grafmueller S, Fleming V, Flint J, Willberg CB, Bengsch B, Seigel B, Ramamurthy N, Zitzmann N, Barnes EJ, Thevanayagam J, Bhagwanani A, Leslie A, Oo YH, Kollnberger S, Bowness P, Drognitz O, Adams DH, Blum HE, Thimme R, Klenerman P. Billerbeck E, et al. Among authors: walker l. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3006-11. doi: 10.1073/pnas.0914839107. Epub 2010 Jan 28. Proc Natl Acad Sci U S A. 2010. PMID: 20133607 Free PMC article.
Human MAIT and CD8αα cells develop from a pool of type-17 precommitted CD8+ T cells.
Walker LJ, Kang YH, Smith MO, Tharmalingham H, Ramamurthy N, Fleming VM, Sahgal N, Leslie A, Oo Y, Geremia A, Scriba TJ, Hanekom WA, Lauer GM, Lantz O, Adams DH, Powrie F, Barnes E, Klenerman P. Walker LJ, et al. Blood. 2012 Jan 12;119(2):422-33. doi: 10.1182/blood-2011-05-353789. Epub 2011 Nov 15. Blood. 2012. PMID: 22086415 Free PMC article.
CD161(int)CD8+ T cells: a novel population of highly functional, memory CD8+ T cells enriched within the gut.
Fergusson JR, Hühn MH, Swadling L, Walker LJ, Kurioka A, Llibre A, Bertoletti A, Holländer G, Newell EW, Davis MM, Sverremark-Ekström E, Powrie F, Capone S, Folgori A, Barnes E, Willberg CB, Ussher JE, Klenerman P. Fergusson JR, et al. Among authors: walker lj. Mucosal Immunol. 2016 Mar;9(2):401-13. doi: 10.1038/mi.2015.69. Epub 2015 Jul 29. Mucosal Immunol. 2016. PMID: 26220166 Free PMC article.
CD161(+)CD4(+) T cells are enriched in the liver during chronic hepatitis and associated with co-secretion of IL-22 and IFN-γ.
Kang YH, Seigel B, Bengsch B, Fleming VM, Billerbeck E, Simmons R, Walker L, Willberg CB, Barnes EJ, Bhagwanani A, Oo YH, Blum HE, Adams DH, Thimme R, Klenerman P. Kang YH, et al. Among authors: walker l. Front Immunol. 2012 Nov 20;3:346. doi: 10.3389/fimmu.2012.00346. eCollection 2012. Front Immunol. 2012. PMID: 23181064 Free PMC article.
T cell sensitivity and the outcome of viral infection.
Walker LJ, Sewell AK, Klenerman P. Walker LJ, et al. Clin Exp Immunol. 2010 Mar;159(3):245-55. doi: 10.1111/j.1365-2249.2009.04047.x. Epub 2009 Dec 1. Clin Exp Immunol. 2010. PMID: 19968665 Free PMC article. Review.
The rise and fall of MAIT cells with age.
Walker LJ, Tharmalingam H, Klenerman P. Walker LJ, et al. Scand J Immunol. 2014 Dec;80(6):462-3. doi: 10.1111/sji.12237. Scand J Immunol. 2014. PMID: 25196940 Free PMC article. No abstract available.
CD161 Defines a Functionally Distinct Subset of Pro-Inflammatory Natural Killer Cells.
Kurioka A, Cosgrove C, Simoni Y, van Wilgenburg B, Geremia A, Björkander S, Sverremark-Ekström E, Thurnheer C, Günthard HF, Khanna N; Swiss HIV Cohort Study; Oxford IBD Cohort Investigators; Walker LJ, Arancibia-Cárcamo CV, Newell EW, Willberg CB, Klenerman P. Kurioka A, et al. Front Immunol. 2018 Apr 9;9:486. doi: 10.3389/fimmu.2018.00486. eCollection 2018. Front Immunol. 2018. PMID: 29686665 Free PMC article.
MAIT cells: new guardians of the liver.
Kurioka A, Walker LJ, Klenerman P, Willberg CB. Kurioka A, et al. Clin Transl Immunology. 2016 Aug 19;5(8):e98. doi: 10.1038/cti.2016.51. eCollection 2016 Aug. Clin Transl Immunology. 2016. PMID: 27588203 Free PMC article. Review.
3,588 results