Frimurer TM - Search Results

1

Exploration of SAR features by modifications of thiazoleacetic acids as CRTH2 antagonists.

Grimstrup M, Receveur JM, Rist Ø, Frimurer TM, Nielsen PA, Mathiesen JM, Högberg T. Grimstrup M, et al. Among authors: frimurer tm. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1638-41. doi: 10.1016/j.bmcl.2010.01.092. Epub 2010 Jan 22. Bioorg Med Chem Lett. 2010. PMID: 20137942

2

A physicogenetic method to assign ligand-binding relationships between 7TM receptors.

Frimurer TM, Ulven T, Elling CE, Gerlach LO, Kostenis E, Högberg T. Frimurer TM, et al. Bioorg Med Chem Lett. 2005 Aug 15;15(16):3707-12. doi: 10.1016/j.bmcl.2005.05.102. Bioorg Med Chem Lett. 2005. PMID: 15993056

3

6-Acylamino-2-aminoquinolines as potent melanin-concentrating hormone 1 receptor antagonists. Identification, structure-activity relationship, and investigation of binding mode.

Ulven T, Frimurer TM, Receveur JM, Little PB, Rist O, Nørregaard PK, Högberg T. Ulven T, et al. Among authors: frimurer tm. J Med Chem. 2005 Sep 8;48(18):5684-97. doi: 10.1021/jm050103y. J Med Chem. 2005. PMID: 16134937

4

6-Acylamino-2-amino-4-methylquinolines as potent melanin-concentrating hormone 1 receptor antagonists: structure-activity exploration of eastern and western parts.

Ulven T, Little PB, Receveur JM, Frimurer TM, Rist O, Nørregaard PK, Högberg T. Ulven T, et al. Among authors: frimurer tm. Bioorg Med Chem Lett. 2006 Feb 15;16(4):1070-5. doi: 10.1016/j.bmcl.2005.10.066. Epub 2005 Nov 10. Bioorg Med Chem Lett. 2006. PMID: 16289819

5

Novel selective orally active CRTH2 antagonists for allergic inflammation developed from in silico derived hits.

Ulven T, Receveur JM, Grimstrup M, Rist Ø, Frimurer TM, Gerlach LO, Mathiesen JM, Kostenis E, Uller L, Högberg T. Ulven T, et al. Among authors: frimurer tm. J Med Chem. 2006 Nov 16;49(23):6638-41. doi: 10.1021/jm060657g. J Med Chem. 2006. PMID: 17154491

6

Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2.

Grimstrup M, Rist Ø, Receveur JM, Frimurer TM, Ulven T, Mathiesen JM, Kostenis E, Högberg T. Grimstrup M, et al. Among authors: frimurer tm. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1181-5. doi: 10.1016/j.bmcl.2009.12.015. Epub 2009 Dec 6. Bioorg Med Chem Lett. 2010. PMID: 20022749

7

Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 1.

Rist Ø, Grimstrup M, Receveur JM, Frimurer TM, Ulven T, Kostenis E, Högberg T. Rist Ø, et al. Among authors: frimurer tm. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1177-80. doi: 10.1016/j.bmcl.2009.12.008. Epub 2009 Dec 4. Bioorg Med Chem Lett. 2010. PMID: 20031403

8

Discovery of novel, orally available benzimidazoles as melanin concentrating hormone receptor 1 (MCHR1) antagonists.

Sasmal PK, Sasmal S, Rao PT, Venkatesham B, Roshaiah M, Abbineni C, Khanna I, Jadhav VP, Suresh J, Talwar R, Muzeeb S, Receveur JM, Frimurer TM, Rist Ø, Elster L, Högberg T. Sasmal PK, et al. Among authors: frimurer tm. Bioorg Med Chem Lett. 2010 Sep 15;20(18):5443-8. doi: 10.1016/j.bmcl.2010.07.086. Epub 2010 Jul 29. Bioorg Med Chem Lett. 2010. PMID: 20724156

9

Drug design of GPCR ligands using physicogenetics and chemogenomics--principles and case studies.

Frimurer TM, Högberg T. Frimurer TM, et al. Curr Top Med Chem. 2011;11(15):1882-901. doi: 10.2174/156802611796391258. Curr Top Med Chem. 2011. PMID: 21470174 Review.

10

Design and optimization of quinazoline derivatives as melanin concentrating hormone receptor 1 (MCHR1) antagonists.

Sasmal S, Balaji G, Kanna Reddy HR, Balasubrahmanyam D, Srinivas G, Kyasa SK, Sasmal PK, Khanna I, Talwar R, Suresh J, Jadhav VP, Muzeeb S, Shashikumar D, Harinder Reddy K, Sebastian VJ, Frimurer TM, Rist Ø, Elster L, Högberg T. Sasmal S, et al. Among authors: frimurer tm. Bioorg Med Chem Lett. 2012 May 1;22(9):3157-62. doi: 10.1016/j.bmcl.2012.03.050. Epub 2012 Mar 23. Bioorg Med Chem Lett. 2012. PMID: 22487182

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