Schaffner W - Search Results

1

Promoters with the octamer DNA motif (ATGCAAAT) can be ubiquitous or cell type-specific depending on binding affinity of the octamer site and Oct-factor concentration.

Kemler I, Bucher E, Seipel K, Müller-Immerglück MM, Schaffner W. Kemler I, et al. Among authors: schaffner w. Nucleic Acids Res. 1991 Jan 25;19(2):237-42. doi: 10.1093/nar/19.2.237. Nucleic Acids Res. 1991. PMID: 2014164 Free PMC article.

2

Astrocytes and glioblastoma cells express novel octamer-DNA binding proteins distinct from the ubiquitous Oct-1 and B cell type Oct-2 proteins.

Schreiber E, Harshman K, Kemler I, Malipiero U, Schaffner W, Fontana A. Schreiber E, et al. Among authors: schaffner w. Nucleic Acids Res. 1990 Sep 25;18(18):5495-503. doi: 10.1093/nar/18.18.5495. Nucleic Acids Res. 1990. PMID: 2216722 Free PMC article.

3

Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cells.

Müller-Immerglück MM, Schaffner W, Matthias P. Müller-Immerglück MM, et al. Among authors: schaffner w. EMBO J. 1990 May;9(5):1625-34. doi: 10.1002/j.1460-2075.1990.tb08282.x. EMBO J. 1990. PMID: 2328728 Free PMC article.

4

Octamer transcription factors and the cell type-specificity of immunoglobulin gene expression.

Kemler I, Schaffner W. Kemler I, et al. Among authors: schaffner w. FASEB J. 1990 Mar;4(5):1444-9. doi: 10.1096/fasebj.4.5.2407588. FASEB J. 1990. PMID: 2407588 Review.

5

Octamer transcription factors bind to two different sequence motifs of the immunoglobulin heavy chain promoter.

Kemler I, Schreiber E, Müller MM, Matthias P, Schaffner W. Kemler I, et al. Among authors: schaffner w. EMBO J. 1989 Jul;8(7):2001-8. doi: 10.1002/j.1460-2075.1989.tb03607.x. EMBO J. 1989. PMID: 2507313 Free PMC article.

6

C-terminal domain (CTD) of RNA-polymerase II and N-terminal segment of the human TATA binding protein (TBP) can mediate remote and proximal transcriptional activation, respectively.

Seipel K, Georgiev O, Gerber HP, Schaffner W. Seipel K, et al. Among authors: schaffner w. Nucleic Acids Res. 1993 Dec 11;21(24):5609-15. doi: 10.1093/nar/21.24.5609. Nucleic Acids Res. 1993. PMID: 8284205 Free PMC article.

7

Different activation domains stimulate transcription from remote ('enhancer') and proximal ('promoter') positions.

Seipel K, Georgiev O, Schaffner W. Seipel K, et al. Among authors: schaffner w. EMBO J. 1992 Dec;11(13):4961-8. doi: 10.1002/j.1460-2075.1992.tb05603.x. EMBO J. 1992. PMID: 1464321 Free PMC article.

8

Basal components of the transcription apparatus (RNA polymerase II, TATA-binding protein) contain activation domains: is the repetitive C-terminal domain (CTD) of RNA polymerase II a "portable enhancer domain"?

Seipel K, Georgiev O, Gerber HP, Schaffner W. Seipel K, et al. Among authors: schaffner w. Mol Reprod Dev. 1994 Oct;39(2):215-25. doi: 10.1002/mrd.1080390215. Mol Reprod Dev. 1994. PMID: 7826625

9

Different potential of cellular and viral activators of transcription revealed in oocytes and early embryos of Xenopus laevis.

Xu L, Rungger D, Georgiev O, Seipel K, Schaffner W. Xu L, et al. Among authors: schaffner w. Biol Chem Hoppe Seyler. 1994 Feb;375(2):105-12. doi: 10.1515/bchm3.1994.375.2.105. Biol Chem Hoppe Seyler. 1994. PMID: 8192855

10

Transcriptional activation modulated by homopolymeric glutamine and proline stretches.

Gerber HP, Seipel K, Georgiev O, Höfferer M, Hug M, Rusconi S, Schaffner W. Gerber HP, et al. Among authors: schaffner w. Science. 1994 Feb 11;263(5148):808-11. doi: 10.1126/science.8303297. Science. 1994. PMID: 8303297

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