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The metabolic syndrome and the liver.
Verrijken A, Francque S, Van Gaal L. Verrijken A, et al. Among authors: francque s. Acta Gastroenterol Belg. 2008 Jan-Mar;71(1):48-59. Acta Gastroenterol Belg. 2008. PMID: 18396752
High prevalence of advanced fibrosis in association with the metabolic syndrome in a Belgian prospective cohort of NAFLD patients with elevated ALT. Results of the Belgian NAFLD registry.
Francque S, De Maeght S, Adler M, Deltenre P, de Galocsy C, Orlent H, Van Steenbergen W, Bastens B, Wain E, Langlet P, Lasser L, Verlinden W, Van Marck E, Henrion J; Steering Committee of the Belgian Association for the Study of the Liver. Francque S, et al. Acta Gastroenterol Belg. 2011 Mar;74(1):9-16. Acta Gastroenterol Belg. 2011. PMID: 21563648 Free article.
A gene variant of PNPLA3, but not of APOC3, is associated with histological parameters of NAFLD in an obese population.
Verrijken A, Beckers S, Francque S, Hilden H, Caron S, Zegers D, Ruppert M, Hubens G, Van Marck E, Michielsen P, Staels B, Taskinen MR, Van Hul W, Van Gaal L. Verrijken A, et al. Among authors: francque s. Obesity (Silver Spring). 2013 Oct;21(10):2138-45. doi: 10.1002/oby.20366. Epub 2013 Jun 6. Obesity (Silver Spring). 2013. PMID: 23512881 Free article.
SULF2 strongly prediposes to fasting and postprandial triglycerides in patients with obesity and type 2 diabetes mellitus.
Hassing HC, Surendran RP, Derudas B, Verrijken A, Francque SM, Mooij HL, Bernelot Moens SJ, Hart LM, Nijpels G, Dekker JM, Williams KJ, Stroes ES, Van Gaal LF, Staels B, Nieuwdorp M, Dallinga-Thie GM. Hassing HC, et al. Among authors: francque sm. Obesity (Silver Spring). 2014 May;22(5):1309-16. doi: 10.1002/oby.20682. Epub 2014 Jan 9. Obesity (Silver Spring). 2014. PMID: 24339435 Free PMC article.
Screening for therapeutic trials and treatment indication in clinical practice: MACK-3, a new blood test for the diagnosis of fibrotic NASH.
Boursier J, Anty R, Vonghia L, Moal V, Vanwolleghem T, Canivet CM, Michalak S, Bonnafous S, Michielsen P, Oberti F, Iannelli A, Van Gaal L, Patouraux S, Blanchet O, Verrijken A, Gual P, Rousselet MC, Driessen A, Hunault G, Bertrais S, Tran A, Calès P, Francque S. Boursier J, et al. Among authors: francque s. Aliment Pharmacol Ther. 2018 May;47(10):1387-1396. doi: 10.1111/apt.14621. Epub 2018 Mar 25. Aliment Pharmacol Ther. 2018. PMID: 29577364 Clinical Trial.
Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα.
Liang N, Damdimopoulos A, Goñi S, Huang Z, Vedin LL, Jakobsson T, Giudici M, Ahmed O, Pedrelli M, Barilla S, Alzaid F, Mendoza A, Schröder T, Kuiper R, Parini P, Hollenberg A, Lefebvre P, Francque S, Van Gaal L, Staels B, Venteclef N, Treuter E, Fan R. Liang N, et al. Among authors: francque s. Nat Commun. 2019 Apr 11;10(1):1684. doi: 10.1038/s41467-019-09524-z. Nat Commun. 2019. PMID: 30975991 Free PMC article.
265 results