Jakobsen BK - Search Results

1

Production of a soluble disulfide bond-linked TCR in the cytoplasm of Escherichia coli trxB gor mutants.

Liddy N, Molloy PE, Bennett AD, Boulter JM, Jakobsen BK, Li Y. Liddy N, et al. Among authors: jakobsen bk. Mol Biotechnol. 2010 Jun;45(2):140-9. doi: 10.1007/s12033-010-9250-0. Mol Biotechnol. 2010. PMID: 20143183

2

Stable, soluble T-cell receptor molecules for crystallization and therapeutics.

Boulter JM, Glick M, Todorov PT, Baston E, Sami M, Rizkallah P, Jakobsen BK. Boulter JM, et al. Among authors: jakobsen bk. Protein Eng. 2003 Sep;16(9):707-11. doi: 10.1093/protein/gzg087. Protein Eng. 2003. PMID: 14560057

3

Directed evolution of human T-cell receptors with picomolar affinities by phage display.

Li Y, Moysey R, Molloy PE, Vuidepot AL, Mahon T, Baston E, Dunn S, Liddy N, Jacob J, Jakobsen BK, Boulter JM. Li Y, et al. Among authors: jakobsen bk. Nat Biotechnol. 2005 Mar;23(3):349-54. doi: 10.1038/nbt1070. Epub 2005 Feb 20. Nat Biotechnol. 2005. PMID: 15723046

4

Soluble T cell receptors: novel immunotherapies.

Molloy PE, Sewell AK, Jakobsen BK. Molloy PE, et al. Among authors: jakobsen bk. Curr Opin Pharmacol. 2005 Aug;5(4):438-43. doi: 10.1016/j.coph.2005.02.004. Curr Opin Pharmacol. 2005. PMID: 15939669 Review.

5

Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.

Dunn SM, Rizkallah PJ, Baston E, Mahon T, Cameron B, Moysey R, Gao F, Sami M, Boulter J, Li Y, Jakobsen BK. Dunn SM, et al. Among authors: jakobsen bk. Protein Sci. 2006 Apr;15(4):710-21. doi: 10.1110/ps.051936406. Protein Sci. 2006. PMID: 16600963 Free PMC article.

6

The HLA A*0201-restricted hTERT(540-548) peptide is not detected on tumor cells by a CTL clone or a high-affinity T-cell receptor.

Purbhoo MA, Li Y, Sutton DH, Brewer JE, Gostick E, Bossi G, Laugel B, Moysey R, Baston E, Liddy N, Cameron B, Bennett AD, Ashfield R, Milicic A, Price DA, Classon BJ, Sewell AK, Jakobsen BK. Purbhoo MA, et al. Among authors: jakobsen bk. Mol Cancer Ther. 2007 Jul;6(7):2081-91. doi: 10.1158/1535-7163.MCT-07-0092. Mol Cancer Ther. 2007. PMID: 17620437 Free article.

7

Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry.

Sami M, Rizkallah PJ, Dunn S, Molloy P, Moysey R, Vuidepot A, Baston E, Todorov P, Li Y, Gao F, Boulter JM, Jakobsen BK. Sami M, et al. Among authors: jakobsen bk. Protein Eng Des Sel. 2007 Aug;20(8):397-403. doi: 10.1093/protein/gzm033. Epub 2007 Jul 20. Protein Eng Des Sel. 2007. PMID: 17644531

8

T cell receptor engagement of peptide-major histocompatibility complex class I does not modify CD8 binding.

Cole DK, Dunn SM, Sami M, Boulter JM, Jakobsen BK, Sewell AK. Cole DK, et al. Among authors: jakobsen bk. Mol Immunol. 2008 May;45(9):2700-9. doi: 10.1016/j.molimm.2007.12.009. Epub 2008 Feb 19. Mol Immunol. 2008. PMID: 18243322

9

Monoclonal TCR-redirected tumor cell killing.

Liddy N, Bossi G, Adams KJ, Lissina A, Mahon TM, Hassan NJ, Gavarret J, Bianchi FC, Pumphrey NJ, Ladell K, Gostick E, Sewell AK, Lissin NM, Harwood NE, Molloy PE, Li Y, Cameron BJ, Sami M, Baston EE, Todorov PT, Paston SJ, Dennis RE, Harper JV, Dunn SM, Ashfield R, Johnson A, McGrath Y, Plesa G, June CH, Kalos M, Price DA, Vuidepot A, Williams DD, Sutton DH, Jakobsen BK. Liddy N, et al. Among authors: jakobsen bk. Nat Med. 2012 Jun;18(6):980-7. doi: 10.1038/nm.2764. Nat Med. 2012. PMID: 22561687

10

Different affinity windows for virus and cancer-specific T-cell receptors: implications for therapeutic strategies.

Aleksic M, Liddy N, Molloy PE, Pumphrey N, Vuidepot A, Chang KM, Jakobsen BK. Aleksic M, et al. Among authors: jakobsen bk. Eur J Immunol. 2012 Dec;42(12):3174-9. doi: 10.1002/eji.201242606. Epub 2012 Oct 16. Eur J Immunol. 2012. PMID: 22949370 Free PMC article.

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