Julien JP - Search Results

1

Ablation of the complementarity-determining region H3 apex of the anti-HIV-1 broadly neutralizing antibody 2F5 abrogates neutralizing capacity without affecting core epitope binding.

Julien JP, Huarte N, Maeso R, Taneva SG, Cunningham A, Nieva JL, Pai EF. Julien JP, et al. J Virol. 2010 May;84(9):4136-47. doi: 10.1128/JVI.02357-09. Epub 2010 Feb 10. J Virol. 2010. PMID: 20147404 Free PMC article.

2

Crystal structure of the complex between the F(ab)' fragment of the cross-neutralizing anti-HIV-1 antibody 2F5 and the F(ab) fragment of its anti-idiotypic antibody 3H6.

Bryson S, Julien JP, Isenman DE, Kunert R, Katinger H, Pai EF. Bryson S, et al. Among authors: julien jp. J Mol Biol. 2008 Oct 17;382(4):910-9. doi: 10.1016/j.jmb.2008.07.057. Epub 2008 Jul 27. J Mol Biol. 2008. PMID: 18692506

3

Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site.

Julien JP, Bryson S, Nieva JL, Pai EF. Julien JP, et al. J Mol Biol. 2008 Dec 12;384(2):377-92. doi: 10.1016/j.jmb.2008.09.024. Epub 2008 Sep 18. J Mol Biol. 2008. PMID: 18824005

4

Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications.

Bryson S, Julien JP, Hynes RC, Pai EF. Bryson S, et al. Among authors: julien jp. J Virol. 2009 Nov;83(22):11862-75. doi: 10.1128/JVI.01604-09. Epub 2009 Sep 9. J Virol. 2009. PMID: 19740978 Free PMC article.

5

Structural constraints imposed by the conserved fusion peptide on the HIV-1 gp41 epitope recognized by the broadly neutralizing antibody 2F5.

de la Arada I, Julien JP, de la Torre BG, Huarte N, Andreu D, Pai EF, Arrondo JL, Nieva JL. de la Arada I, et al. Among authors: julien jp. J Phys Chem B. 2009 Oct 15;113(41):13626-37. doi: 10.1021/jp905965h. J Phys Chem B. 2009. PMID: 19754136

6

Interaction of anti-HIV type 1 antibody 2F5 with phospholipid bilayers and its relevance for the mechanism of virus neutralization.

Maeso R, Huarte N, Julien JP, Kunert R, Pai EF, Nieva JL. Maeso R, et al. Among authors: julien jp. AIDS Res Hum Retroviruses. 2011 Aug;27(8):863-76. doi: 10.1089/AID.2010.0265. Epub 2011 Jan 15. AIDS Res Hum Retroviruses. 2011. PMID: 21142698

7

Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope.

Azoitei ML, Ban YE, Julien JP, Bryson S, Schroeter A, Kalyuzhniy O, Porter JR, Adachi Y, Baker D, Pai EF, Schief WR. Azoitei ML, et al. Among authors: julien jp. J Mol Biol. 2012 Jan 6;415(1):175-92. doi: 10.1016/j.jmb.2011.10.003. Epub 2011 Oct 31. J Mol Biol. 2012. PMID: 22061265 Free PMC article.

8

Neutralizing epitopes in the membrane-proximal external region of HIV-1 gp41 are influenced by the transmembrane domain and the plasma membrane.

Montero M, Gulzar N, Klaric KA, Donald JE, Lepik C, Wu S, Tsai S, Julien JP, Hessell AJ, Wang S, Lu S, Burton DR, Pai EF, Degrado WF, Scott JK. Montero M, et al. Among authors: julien jp. J Virol. 2012 Mar;86(6):2930-41. doi: 10.1128/JVI.06349-11. Epub 2012 Jan 11. J Virol. 2012. PMID: 22238313 Free PMC article.

9

Structural characterization of cleaved, soluble HIV-1 envelope glycoprotein trimers.

Khayat R, Lee JH, Julien JP, Cupo A, Klasse PJ, Sanders RW, Moore JP, Wilson IA, Ward AB. Khayat R, et al. Among authors: julien jp. J Virol. 2013 Sep;87(17):9865-72. doi: 10.1128/JVI.01222-13. Epub 2013 Jul 3. J Virol. 2013. PMID: 23824817 Free PMC article.

10

EspP, an Extracellular Serine Protease from Enterohemorrhagic E. coli, Reduces Coagulation Factor Activities, Reduces Clot Strength, and Promotes Clot Lysis.

Kuo KH, Khan S, Rand ML, Mian HS, Brnjac E, Sandercock LE, Akula I, Julien JP, Pai EF, Chesney AE. Kuo KH, et al. Among authors: julien jp. PLoS One. 2016 Mar 2;11(3):e0149830. doi: 10.1371/journal.pone.0149830. eCollection 2016. PLoS One. 2016. PMID: 26934472 Free PMC article.

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