Pallis M - Search Results

1

The FLT3 internal tandem duplication mutation is a secondary target of the aurora B kinase inhibitor AZD1152-HQPA in acute myelogenous leukemia cells.

Grundy M, Seedhouse C, Shang S, Richardson J, Russell N, Pallis M. Grundy M, et al. Among authors: pallis m. Mol Cancer Ther. 2010 Mar;9(3):661-72. doi: 10.1158/1535-7163.MCT-09-1144. Epub 2010 Feb 16. Mol Cancer Ther. 2010. PMID: 20159992

2

Resistance to spontaneous apoptosis in acute myeloid leukaemia blasts is associated with p-glycoprotein expression and function, but not with the presence of FLT3 internal tandem duplications.

Pallis M, Turzanski J, Grundy M, Seedhouse C, Russell N. Pallis M, et al. Br J Haematol. 2003 Mar;120(6):1009-16. doi: 10.1046/j.1365-2141.2003.04210.x. Br J Haematol. 2003. PMID: 12648071 Free article.

3

Flow cytometric measurement of phosphorylated STAT5 in AML: lack of specific association with FLT3 internal tandem duplications.

Pallis M, Seedhouse C, Grundy M, Russell N. Pallis M, et al. Leuk Res. 2003 Sep;27(9):803-5. doi: 10.1016/s0145-2126(03)00012-2. Leuk Res. 2003. PMID: 12804638

4

The expression of P-glycoprotein in AML cells with FLT3 internal tandem duplications is associated with reduced apoptosis in response to FLT3 inhibitors.

Hunter HM, Pallis M, Seedhouse CH, Grundy M, Gray C, Russell NH. Hunter HM, et al. Among authors: pallis m. Br J Haematol. 2004 Oct;127(1):26-33. doi: 10.1111/j.1365-2141.2004.05145.x. Br J Haematol. 2004. PMID: 15384974 Free article.

5

FLT3-ITD expression levels and their effect on STAT5 in AML with and without NPM mutations.

Seedhouse CH, Pallis M, Grundy M, Shang S, Russell NH. Seedhouse CH, et al. Among authors: pallis m. Br J Haematol. 2009 Dec;147(5):653-61. doi: 10.1111/j.1365-2141.2009.07901.x. Epub 2009 Sep 22. Br J Haematol. 2009. PMID: 19775300 Free article.

6

Impaired S-phase arrest in acute myeloid leukemia cells with a FLT3 internal tandem duplication treated with clofarabine.

Seedhouse C, Grundy M, Shang S, Ronan J, Pimblett H, Russell N, Pallis M. Seedhouse C, et al. Among authors: pallis m. Clin Cancer Res. 2009 Dec 1;15(23):7291-8. doi: 10.1158/1078-0432.CCR-09-1222. Epub 2009 Nov 24. Clin Cancer Res. 2009. PMID: 19934300

7

P-glycoprotein and breast cancer resistance protein in acute myeloid leukaemia cells treated with the aurora-B kinase inhibitor barasertib-hQPA.

Grundy M, Seedhouse C, Russell NH, Pallis M. Grundy M, et al. Among authors: pallis m. BMC Cancer. 2011 Jun 16;11:254. doi: 10.1186/1471-2407-11-254. BMC Cancer. 2011. PMID: 21679421 Free PMC article.

8

The multi-kinase inhibitor TG02 overcomes signalling activation by survival factors to deplete MCL1 and XIAP and induce cell death in primary acute myeloid leukaemia cells.

Pallis M, Abdul-Aziz A, Burrows F, Seedhouse C, Grundy M, Russell N. Pallis M, et al. Br J Haematol. 2012 Oct;159(2):191-203. doi: 10.1111/bjh.12018. Epub 2012 Aug 30. Br J Haematol. 2012. PMID: 22934750 Free article. Clinical Trial.

9

Targeting of CD34+CD38- cells using Gemtuzumab ozogamicin (Mylotarg) in combination with tipifarnib (Zarnestra) in Acute Myeloid Leukaemia.

Jawad M, Yu N, Seedhouse C, Tandon K, Russell NH, Pallis M. Jawad M, et al. Among authors: pallis m. BMC Cancer. 2012 Sep 26;12:431. doi: 10.1186/1471-2407-12-431. BMC Cancer. 2012. PMID: 23013471 Free PMC article.

10

Distinct poor prognostic subgroups of acute myeloid leukaemia, FLT3-ITD and P-glycoprotein-positive, have contrasting levels of FOXO1.

Seedhouse CH, Mills KI, Ahluwalia S, Grundy M, Shang S, Burnett AK, Russell NH, Pallis M. Seedhouse CH, et al. Among authors: pallis m. Leuk Res. 2014 Jan;38(1):131-7. doi: 10.1016/j.leukres.2013.10.030. Epub 2013 Nov 8. Leuk Res. 2014. PMID: 24268349

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