Piizzi G - Search Results

1

Observations in the Synthesis of the Core of the Antitumor Illudins via an Enyne Ring Closing Metathesis Cascade.

Movassaghi M, Piizzi G, Siegel DS, Piersanti G. Movassaghi M, et al. Among authors: piizzi g. Tetrahedron Lett. 2009 Sep 30;50(39):5489-5492. doi: 10.1016/j.tetlet.2009.07.102. Tetrahedron Lett. 2009. PMID: 20160945 Free PMC article.

2

Enantioselective total synthesis of (-)-acylfulvene and (-)-irofulven.

Movassaghi M, Piizzi G, Siegel DS, Piersanti G. Movassaghi M, et al. Among authors: piizzi g. Angew Chem Int Ed Engl. 2006 Sep 4;45(35):5859-63. doi: 10.1002/anie.200602011. Angew Chem Int Ed Engl. 2006. PMID: 16888819 No abstract available.

3

Enantioselective total synthesis of (-)-acylfulvene and (-)-irofulven.

Siegel DS, Piizzi G, Piersanti G, Movassaghi M. Siegel DS, et al. Among authors: piizzi g. J Org Chem. 2009 Dec 18;74(24):9292-304. doi: 10.1021/jo901926z. J Org Chem. 2009. PMID: 19938810 Free PMC article.

4

First synthesis of the A/B ring of ouabain.

Jung ME, Piizzi G. Jung ME, et al. Among authors: piizzi g. Org Lett. 2003 Jan 23;5(2):137-40. doi: 10.1021/ol0270881. Org Lett. 2003. PMID: 12529124

5

Bacterial Autoimmune Drug Metabolism Transforms an Immunomodulator into Structurally and Functionally Divergent Antibiotics.

Park HB, Goddard TN, Oh J, Patel J, Wei Z, Perez CE, Mercado BQ, Wang R, Wyche TP, Piizzi G, Flavell RA, Crawford JM. Park HB, et al. Among authors: piizzi g. Angew Chem Int Ed Engl. 2020 May 11;59(20):7871-7880. doi: 10.1002/anie.201916204. Epub 2020 Mar 17. Angew Chem Int Ed Engl. 2020. PMID: 32097515 Free PMC article.

6

Novel rearrangements of 4-silyl-3-buten-2-ones.

Jung ME, Piizzi G. Jung ME, et al. Among authors: piizzi g. J Org Chem. 2002 May 31;67(11):3911-4. doi: 10.1021/jo0109467. J Org Chem. 2002. PMID: 12027713

7

Synthetic approach to the AB ring system of ouabain.

Jung ME, Piizzi G. Jung ME, et al. Among authors: piizzi g. J Org Chem. 2003 Apr 4;68(7):2572-82. doi: 10.1021/jo020454+. J Org Chem. 2003. PMID: 12662025

8

gem-disubstituent effect: theoretical basis and synthetic applications.

Jung ME, Piizzi G. Jung ME, et al. Among authors: piizzi g. Chem Rev. 2005 May;105(5):1735-66. doi: 10.1021/cr940337h. Chem Rev. 2005. PMID: 15884788 Review. No abstract available.

9

Discovery of a Brain-Penetrant ATP-Competitive Inhibitor of the Mechanistic Target of Rapamycin (mTOR) for CNS Disorders.

Bonazzi S, Goold CP, Gray A, Thomsen NM, Nunez J, Karki RG, Gorde A, Biag JD, Malik HA, Sun Y, Liang G, Lubicka D, Salas S, Labbe-Giguere N, Keaney EP, McTighe S, Liu S, Deng L, Piizzi G, Lombardo F, Burdette D, Dodart JC, Wilson CJ, Peukert S, Curtis D, Hamann LG, Murphy LO. Bonazzi S, et al. Among authors: piizzi g. J Med Chem. 2020 Feb 13;63(3):1068-1083. doi: 10.1021/acs.jmedchem.9b01398. Epub 2020 Jan 31. J Med Chem. 2020. PMID: 31955578

10

Nicotinamide Phosphoribosyltransferase Inhibitor as a Novel Payload for Antibody-Drug Conjugates.

Karpov AS, Abrams T, Clark S, Raikar A, D'Alessio JA, Dillon MP, Gesner TG, Jones D, Lacaud M, Mallet W, Martyniuk P, Meredith E, Mohseni M, Nieto-Oberhuber CM, Palacios D, Perruccio F, Piizzi G, Zurini M, Bialucha CU. Karpov AS, et al. Among authors: piizzi g. ACS Med Chem Lett. 2018 Jun 28;9(8):838-842. doi: 10.1021/acsmedchemlett.8b00254. eCollection 2018 Aug 9. ACS Med Chem Lett. 2018. PMID: 30128077 Free PMC article.

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