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Variations in DNA elucidate molecular networks that cause disease.
Chen Y, Zhu J, Lum PY, Yang X, Pinto S, MacNeil DJ, Zhang C, Lamb J, Edwards S, Sieberts SK, Leonardson A, Castellini LW, Wang S, Champy MF, Zhang B, Emilsson V, Doss S, Ghazalpour A, Horvath S, Drake TA, Lusis AJ, Schadt EE. Chen Y, et al. Nature. 2008 Mar 27;452(7186):429-35. doi: 10.1038/nature06757. Epub 2008 Mar 16. Nature. 2008. PMID: 18344982 Free PMC article.
The CSF-1-receptor inhibitor, JNJ-40346527 (PRV-6527), reduced inflammatory macrophage recruitment to the intestinal mucosa and suppressed murine T cell mediated colitis.
Manthey CL, Moore BA, Chen Y, Loza MJ, Yao X, Liu H, Belkowski SM, Raymond-Parks H, Dunford PJ, Leon F, Towne JE, Plevy SE. Manthey CL, et al. Among authors: chen y. PLoS One. 2019 Nov 11;14(11):e0223918. doi: 10.1371/journal.pone.0223918. eCollection 2019. PLoS One. 2019. PMID: 31710624 Free PMC article.
Impact of C-MYC/BCL2 Double Expression on Survival Outcomes After Autologous Transplantation in Relapsed/Refractory Diffuse Large B Cell Lymphoma-A Nationwide Retrospective Analysis in Singapore.
Tan JY, Ling VWT, Ng LCK, Krisnadi C, Tan MSY, Grigoropoulos NF, Ong SY, Nagarajan C, Quek JKS, Than H, Lee J, Chan E, Tan LK, Hwang WYK, Goh YT, Linn YC, Koh LP, Ho AYL, Lim FWI, Poon ML, Chen Y. Tan JY, et al. Among authors: chen y. Hematol Oncol. 2025 Jan;43(1):e70030. doi: 10.1002/hon.70030. Hematol Oncol. 2025. PMID: 39729576 No abstract available.
Standard: Human gastric cancer organoids.
Tan R, Hong F, Wang T, Zhong N, Zhao H, Xu RH, Shen L, Liu Y, Yao X, Xiang D, Gao D, Xiong J, Hui L, Zhao B, Miao Z, Hao J, Li Y, Hu S, Fu B, Hua G, Wang L, Zeng ZL, Chen C, Wu J, Wang C, Wang C, Zhan X, Song C, Sun Z, Yu C, Yang Y, Niu G, Wang Y, Zhao T, Chen YG. Tan R, et al. Among authors: chen yg. Cell Regen. 2024 Dec 27;13(1):33. doi: 10.1186/s13619-024-00217-7. Cell Regen. 2024. PMID: 39729207
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