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Acadesine inhibits tissue factor induction and thrombus formation by activating the phosphoinositide 3-kinase/Akt signaling pathway.
Zhang W, Wang J, Wang H, Tang R, Belcher JD, Viollet B, Geng JG, Zhang C, Wu C, Slungaard A, Zhu C, Huo Y. Zhang W, et al. Among authors: slungaard a. Arterioscler Thromb Vasc Biol. 2010 May;30(5):1000-6. doi: 10.1161/ATVBAHA.110.203141. Epub 2010 Feb 25. Arterioscler Thromb Vasc Biol. 2010. PMID: 20185792 Free PMC article.
The HDAC inhibitors trichostatin A and suberoylanilide hydroxamic acid exhibit multiple modalities of benefit for the vascular pathobiology of sickle transgenic mice.
Hebbel RP, Vercellotti GM, Pace BS, Solovey AN, Kollander R, Abanonu CF, Nguyen J, Vineyard JV, Belcher JD, Abdulla F, Osifuye S, Eaton JW, Kelm RJ Jr, Slungaard A. Hebbel RP, et al. Among authors: slungaard a. Blood. 2010 Mar 25;115(12):2483-90. doi: 10.1182/blood-2009-02-204990. Epub 2010 Jan 6. Blood. 2010. PMID: 20053759 Free PMC article.
56 results