Posy S - Search Results

1

T-cadherin structures reveal a novel adhesive binding mechanism.

Ciatto C, Bahna F, Zampieri N, VanSteenhouse HC, Katsamba PS, Ahlsen G, Harrison OJ, Brasch J, Jin X, Posy S, Vendome J, Ranscht B, Jessell TM, Honig B, Shapiro L. Ciatto C, et al. Among authors: posy s. Nat Struct Mol Biol. 2010 Mar;17(3):339-47. doi: 10.1038/nsmb.1781. Epub 2010 Feb 28. Nat Struct Mol Biol. 2010. PMID: 20190755 Free PMC article.

2

Linking molecular affinity and cellular specificity in cadherin-mediated adhesion.

Katsamba P, Carroll K, Ahlsen G, Bahna F, Vendome J, Posy S, Rajebhosale M, Price S, Jessell TM, Ben-Shaul A, Shapiro L, Honig BH. Katsamba P, et al. Among authors: posy s. Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11594-9. doi: 10.1073/pnas.0905349106. Epub 2009 Jun 24. Proc Natl Acad Sci U S A. 2009. PMID: 19553217 Free PMC article.

3

Sequence and structural determinants of strand swapping in cadherin domains: do all cadherins bind through the same adhesive interface?

Posy S, Shapiro L, Honig B. Posy S, et al. J Mol Biol. 2008 May 9;378(4):954-68. doi: 10.1016/j.jmb.2008.02.063. Epub 2008 Mar 4. J Mol Biol. 2008. PMID: 18395225 Free PMC article.

4

Molecular design principles underlying β-strand swapping in the adhesive dimerization of cadherins.

Vendome J, Posy S, Jin X, Bahna F, Ahlsen G, Shapiro L, Honig B. Vendome J, et al. Among authors: posy s. Nat Struct Mol Biol. 2011 Jun;18(6):693-700. doi: 10.1038/nsmb.2051. Epub 2011 May 15. Nat Struct Mol Biol. 2011. PMID: 21572446 Free PMC article.

5

Specificity of cell-cell adhesion by classical cadherins: Critical role for low-affinity dimerization through beta-strand swapping.

Chen CP, Posy S, Ben-Shaul A, Shapiro L, Honig BH. Chen CP, et al. Among authors: posy s. Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8531-6. doi: 10.1073/pnas.0503319102. Epub 2005 Jun 3. Proc Natl Acad Sci U S A. 2005. PMID: 15937105 Free PMC article.

6

On the role of structural information in remote homology detection and sequence alignment: new methods using hybrid sequence profiles.

Tang CL, Xie L, Koh IY, Posy S, Alexov E, Honig B. Tang CL, et al. Among authors: posy s. J Mol Biol. 2003 Dec 12;334(5):1043-62. doi: 10.1016/j.jmb.2003.10.025. J Mol Biol. 2003. PMID: 14643665

7

Crystal structure of the extracellular cholinesterase-like domain from neuroligin-2.

Koehnke J, Jin X, Budreck EC, Posy S, Scheiffele P, Honig B, Shapiro L. Koehnke J, et al. Among authors: posy s. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1873-8. doi: 10.1073/pnas.0711701105. Epub 2008 Feb 4. Proc Natl Acad Sci U S A. 2008. PMID: 18250328 Free PMC article.

8

Searching for neuronal left/right asymmetry: genomewide analysis of nematode receptor-type guanylyl cyclases.

Ortiz CO, Etchberger JF, Posy SL, Frøkjaer-Jensen C, Lockery S, Honig B, Hobert O. Ortiz CO, et al. Among authors: posy sl. Genetics. 2006 May;173(1):131-49. doi: 10.1534/genetics.106.055749. Epub 2006 Mar 17. Genetics. 2006. PMID: 16547101 Free PMC article.

9

MDFit: automated molecular simulations workflow enables high throughput assessment of ligands-protein dynamics.

Brueckner AC, Shields B, Kirubakaran P, Suponya A, Panda M, Posy SL, Johnson S, Lakkaraju SK. Brueckner AC, et al. Among authors: posy sl. J Comput Aided Mol Des. 2024 Jul 17;38(1):24. doi: 10.1007/s10822-024-00564-2. J Comput Aided Mol Des. 2024. PMID: 39014286

10

Discovery of Potent and Selective Quinoxaline-Based Protease-Activated Receptor 4 (PAR4) Antagonists for the Prevention of Arterial Thrombosis.

Zhang X, Jiang W, Richter JM, Bates JA, Reznik SK, Stachura S, Rampulla R, Doddalingappa D, Ulaganathan S, Hua J, Bostwick JS, Sum C, Posy S, Malmstrom S, Dickey J, Harden D, Lawrence RM, Guarino VR, Schumacher WA, Wong P, Yang J, Gordon DA, Wexler RR, Priestley ES. Zhang X, et al. Among authors: posy s. J Med Chem. 2024 Mar 14;67(5):3571-3589. doi: 10.1021/acs.jmedchem.3c01986. Epub 2024 Feb 22. J Med Chem. 2024. PMID: 38385264

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