Gaestel M - Search Results

1

Cross-regulation of cytokine signalling: pro-inflammatory cytokines restrict IL-6 signalling through receptor internalisation and degradation.

Radtke S, Wüller S, Yang XP, Lippok BE, Mütze B, Mais C, de Leur HS, Bode JG, Gaestel M, Heinrich PC, Behrmann I, Schaper F, Hermanns HM. Radtke S, et al. Among authors: gaestel m. J Cell Sci. 2010 Mar 15;123(Pt 6):947-59. doi: 10.1242/jcs.065326. J Cell Sci. 2010. PMID: 20200229 Free article.

2

The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.

Winzen R, Kracht M, Ritter B, Wilhelm A, Chen CY, Shyu AB, Müller M, Gaestel M, Resch K, Holtmann H. Winzen R, et al. Among authors: gaestel m. EMBO J. 1999 Sep 15;18(18):4969-80. doi: 10.1093/emboj/18.18.4969. EMBO J. 1999. PMID: 10487749 Free PMC article.

3

MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis.

Kotlyarov A, Neininger A, Schubert C, Eckert R, Birchmeier C, Volk HD, Gaestel M. Kotlyarov A, et al. Among authors: gaestel m. Nat Cell Biol. 1999 Jun;1(2):94-7. doi: 10.1038/10061. Nat Cell Biol. 1999. PMID: 10559880

4

Scaffolding by ERK3 regulates MK5 in development.

Schumacher S, Laass K, Kant S, Shi Y, Visel A, Gruber AD, Kotlyarov A, Gaestel M. Schumacher S, et al. Among authors: gaestel m. EMBO J. 2004 Dec 8;23(24):4770-9. doi: 10.1038/sj.emboj.7600467. Epub 2004 Nov 11. EMBO J. 2004. PMID: 15538386 Free PMC article.

5

MAPKAP kinases - MKs - two's company, three's a crowd.

Gaestel M. Gaestel M. Nat Rev Mol Cell Biol. 2006 Feb;7(2):120-30. doi: 10.1038/nrm1834. Nat Rev Mol Cell Biol. 2006. PMID: 16421520 Review.

6

Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5.

Kant S, Schumacher S, Singh MK, Kispert A, Kotlyarov A, Gaestel M. Kant S, et al. Among authors: gaestel m. J Biol Chem. 2006 Nov 17;281(46):35511-9. doi: 10.1074/jbc.M606693200. Epub 2006 Sep 13. J Biol Chem. 2006. PMID: 16973613 Free article.

7

Regulation of suppressor of cytokine signaling 3 (SOCS3) mRNA stability by TNF-alpha involves activation of the MKK6/p38MAPK/MK2 cascade.

Ehlting C, Lai WS, Schaper F, Brenndörfer ED, Matthes RJ, Heinrich PC, Ludwig S, Blackshear PJ, Gaestel M, Häussinger D, Bode JG. Ehlting C, et al. Among authors: gaestel m. J Immunol. 2007 Mar 1;178(5):2813-26. doi: 10.4049/jimmunol.178.5.2813. J Immunol. 2007. PMID: 17312125

8

MAPKAP kinase 2-deficiency prevents neurons from cell death by reducing neuroinflammation--relevance in a mouse model of Parkinson's disease.

Thomas T, Timmer M, Cesnulevicius K, Hitti E, Kotlyarov A, Gaestel M. Thomas T, et al. Among authors: gaestel m. J Neurochem. 2008 Jun;105(5):2039-52. doi: 10.1111/j.1471-4159.2008.05310.x. Epub 2008 Feb 22. J Neurochem. 2008. PMID: 18298661 Free article.

9

Distinct functions of the mitogen-activated protein kinase-activated protein (MAPKAP) kinases MK2 and MK3: MK2 mediates lipopolysaccharide-induced signal transducers and activators of transcription 3 (STAT3) activation by preventing negative regulatory effects of MK3.

Ehlting C, Ronkina N, Böhmer O, Albrecht U, Bode KA, Lang KS, Kotlyarov A, Radzioch D, Gaestel M, Häussinger D, Bode JG. Ehlting C, et al. Among authors: gaestel m. J Biol Chem. 2011 Jul 8;286(27):24113-24. doi: 10.1074/jbc.M111.235275. Epub 2011 May 17. J Biol Chem. 2011. PMID: 21586572 Free PMC article.

10

The p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation.

Tiedje C, Ronkina N, Tehrani M, Dhamija S, Laass K, Holtmann H, Kotlyarov A, Gaestel M. Tiedje C, et al. Among authors: gaestel m. PLoS Genet. 2012 Sep;8(9):e1002977. doi: 10.1371/journal.pgen.1002977. Epub 2012 Sep 27. PLoS Genet. 2012. PMID: 23028373 Free PMC article.

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