Hargreaves IP - Search Results

1

Molecular and phenotypic characterization of a mouse model of oculopharyngeal muscular dystrophy reveals severe muscular atrophy restricted to fast glycolytic fibres.

Trollet C, Anvar SY, Venema A, Hargreaves IP, Foster K, Vignaud A, Ferry A, Negroni E, Hourde C, Baraibar MA, 't Hoen PA, Davies JE, Rubinsztein DC, Heales SJ, Mouly V, van der Maarel SM, Butler-Browne G, Raz V, Dickson G. Trollet C, et al. Among authors: hargreaves ip. Hum Mol Genet. 2010 Jun 1;19(11):2191-207. doi: 10.1093/hmg/ddq098. Epub 2010 Mar 5. Hum Mol Genet. 2010. PMID: 20207626

2

Phenotypic variability of mitochondrial disease caused by a nuclear mutation in complex II.

Pagnamenta AT, Hargreaves IP, Duncan AJ, Taanman JW, Heales SJ, Land JM, Bitner-Glindzicz M, Leonard JV, Rahman S. Pagnamenta AT, et al. Among authors: hargreaves ip. Mol Genet Metab. 2006 Nov;89(3):214-21. doi: 10.1016/j.ymgme.2006.05.003. Epub 2006 Jun 23. Mol Genet Metab. 2006. PMID: 16798039

3

Mitochondrial disease: a historical, biochemical, and London perspective.

Land JM, Morgan-Hughes JA, Hargreaves I, Heales SJ. Land JM, et al. Neurochem Res. 2004 Mar;29(3):483-91. doi: 10.1023/b:nere.0000014819.53972.b0. Neurochem Res. 2004. PMID: 15038596 Review.

4

Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations.

Pollard PJ, Brière JJ, Alam NA, Barwell J, Barclay E, Wortham NC, Hunt T, Mitchell M, Olpin S, Moat SJ, Hargreaves IP, Heales SJ, Chung YL, Griffiths JR, Dalgleish A, McGrath JA, Gleeson MJ, Hodgson SV, Poulsom R, Rustin P, Tomlinson IP. Pollard PJ, et al. Among authors: hargreaves ip. Hum Mol Genet. 2005 Aug 1;14(15):2231-9. doi: 10.1093/hmg/ddi227. Epub 2005 Jun 29. Hum Mol Genet. 2005. PMID: 15987702

5

Decreased ubiquinone availability and impaired mitochondrial cytochrome oxidase activity associated with statin treatment.

Duncan AJ, Hargreaves IP, Damian MS, Land JM, Heales SJ. Duncan AJ, et al. Among authors: hargreaves ip. Toxicol Mech Methods. 2009 Jan;19(1):44-50. doi: 10.1080/15376510802305047. Toxicol Mech Methods. 2009. PMID: 19778232

6

Mitochondrial respiratory chain defects are not accompanied by an increase in the activities of lactate dehydrogenase or manganese superoxide dismutase in paediatric skeletal muscle biopsies.

Hargreaves IP, Heales SJ, Land JM. Hargreaves IP, et al. J Inherit Metab Dis. 1999 Dec;22(8):925-31. doi: 10.1023/a:1005643508075. J Inherit Metab Dis. 1999. PMID: 10604144

7

Determination of coenzyme Q10 status in blood mononuclear cells, skeletal muscle, and plasma by HPLC with di-propoxy-coenzyme Q10 as an internal standard.

Duncan AJ, Heales SJ, Mills K, Eaton S, Land JM, Hargreaves IP. Duncan AJ, et al. Among authors: hargreaves ip. Clin Chem. 2005 Dec;51(12):2380-2. doi: 10.1373/clinchem.2005.054643. Clin Chem. 2005. PMID: 16306103 No abstract available.

8

Assessment of Mitochondrial Dysfunction in Experimental Autoimmune Encephalomyelitis (EAE) Models of Multiple Sclerosis.

Ng X, Sadeghian M, Heales S, Hargreaves IP. Ng X, et al. Among authors: hargreaves ip. Int J Mol Sci. 2019 Oct 9;20(20):4975. doi: 10.3390/ijms20204975. Int J Mol Sci. 2019. PMID: 31600882 Free PMC article.

9

Glutathione deficiency in patients with mitochondrial disease: implications for pathogenesis and treatment.

Hargreaves IP, Sheena Y, Land JM, Heales SJ. Hargreaves IP, et al. J Inherit Metab Dis. 2005;28(1):81-8. doi: 10.1007/s10545-005-4160-1. J Inherit Metab Dis. 2005. PMID: 15702408

10

The effect of HMG-CoA reductase inhibitors on coenzyme Q10: possible biochemical/clinical implications.

Hargreaves IP, Duncan AJ, Heales SJ, Land JM. Hargreaves IP, et al. Drug Saf. 2005;28(8):659-76. doi: 10.2165/00002018-200528080-00002. Drug Saf. 2005. PMID: 16048353 Review.

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