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Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT.
Dubreuil P, Letard S, Ciufolini M, Gros L, Humbert M, Castéran N, Borge L, Hajem B, Lermet A, Sippl W, Voisset E, Arock M, Auclair C, Leventhal PS, Mansfield CD, Moussy A, Hermine O. Dubreuil P, et al. Among authors: humbert m. PLoS One. 2009 Sep 30;4(9):e7258. doi: 10.1371/journal.pone.0007258. PLoS One. 2009. PMID: 19789626 Free PMC article.
Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology.
Hammam K, Saez-Ayala M, Rebuffet E, Gros L, Lopez S, Hajem B, Humbert M, Baudelet E, Audebert S, Betzi S, Lugari A, Combes S, Letard S, Casteran N, Mansfield C, Moussy A, De Sepulveda P, Morelli X, Dubreuil P. Hammam K, et al. Among authors: humbert m. Nat Commun. 2017 Nov 10;8(1):1420. doi: 10.1038/s41467-017-01582-5. Nat Commun. 2017. PMID: 29127277 Free PMC article.
Rapamycin inhibits growth and survival of D816V-mutated c-kit mast cells.
Gabillot-Carré M, Lepelletier Y, Humbert M, de Sepuvelda P, Hamouda NB, Zappulla JP, Liblau R, Ribadeau-Dumas A, Machavoine F, Letard S, Baude C, Hermant A, Yang Y, Vargaftig J, Bodemer C, Morelon E, Lortholary O, Recher C, Laurent G, Dy M, Arock M, Dubreuil P, Hermine O. Gabillot-Carré M, et al. Among authors: humbert m. Blood. 2006 Aug 1;108(3):1065-72. doi: 10.1182/blood-2005-06-2433. Epub 2006 Apr 4. Blood. 2006. PMID: 16597595 Free article.
PKD1 is a potential biomarker and therapeutic target in triple-negative breast cancer.
Spasojevic C, Marangoni E, Vacher S, Assayag F, Meseure D, Château-Joubert S, Humbert M, Karam M, Ricort JM, Auclair C, Regairaz M, Bièche I. Spasojevic C, et al. Among authors: humbert m. Oncotarget. 2018 May 1;9(33):23208-23219. doi: 10.18632/oncotarget.25292. eCollection 2018 May 1. Oncotarget. 2018. PMID: 29796183 Free PMC article.
[Geriatrics. Focus on neurocognitive disorders].
Major K, Bosshard Taroni W, Fratangelo L, Humbert M, Lorusso G, D'Amelio P. Major K, et al. Among authors: humbert m. Rev Med Suisse. 2025 Jan 15;21(900-1):30-33. doi: 10.53738/REVMED.2025.21.900-1.30. Rev Med Suisse. 2025. PMID: 39812282 French.
Efficacy and safety of sotatercept across ranges of cardiac index in patients with pulmonary arterial hypertension: A pooled analysis of PULSAR and STELLAR.
Gomberg-Maitland M, Badesch DB, Gibbs JSR, Grünig E, Hoeper MM, Humbert M, Kopeć G, McLaughlin VV, Meyer G, Olsson KM, Preston IR, Rosenkranz S, Souza R, Waxman AB, Perchenet L, Strait J, Xing A, Johnson-Levonas AO, Cornell AG, de Oliveira Pena J, Ardeschir Ghofrani H. Gomberg-Maitland M, et al. Among authors: humbert m. J Heart Lung Transplant. 2024 Dec 5:S1053-2498(24)02009-6. doi: 10.1016/j.healun.2024.11.037. Online ahead of print. J Heart Lung Transplant. 2024. PMID: 39645016
1,402 results