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Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness.
Mathsyaraja H, Catchpole J, Freie B, Eastwood E, Babaeva E, Geuenich M, Cheng PF, Ayers J, Yu M, Wu N, Moorthi S, Poudel KR, Koehne A, Grady W, Houghton AM, Berger AH, Shiio Y, MacPherson D, Eisenman RN. Mathsyaraja H, et al. Among authors: eastwood e. Elife. 2021 Jul 8;10:e64212. doi: 10.7554/eLife.64212. Elife. 2021. PMID: 34236315 Free PMC article.
Co-occupancy identifies transcription factor co-operation for axon growth.
Venkatesh I, Mehra V, Wang Z, Simpson MT, Eastwood E, Chakraborty A, Beine Z, Gross D, Cabahug M, Olson G, Blackmore MG. Venkatesh I, et al. Among authors: eastwood e. Nat Commun. 2021 May 5;12(1):2555. doi: 10.1038/s41467-021-22828-3. Nat Commun. 2021. PMID: 33953205 Free PMC article.
MYCN drives chemoresistance in small cell lung cancer while USP7 inhibition can restore chemosensitivity.
Grunblatt E, Wu N, Zhang H, Liu X, Norton JP, Ohol Y, Leger P, Hiatt JB, Eastwood EC, Thomas R, Ibrahim AH, Jia D, Basom R, Eaton KD, Martins R, Houghton AM, MacPherson D. Grunblatt E, et al. Among authors: eastwood ec. Genes Dev. 2020 Sep 1;34(17-18):1210-1226. doi: 10.1101/gad.340133.120. Epub 2020 Aug 20. Genes Dev. 2020. PMID: 32820040 Free PMC article.
47 results