Pepper C - Search Results

1

CD38 increases CXCL12-mediated signals and homing of chronic lymphocytic leukemia cells.

Vaisitti T, Aydin S, Rossi D, Cottino F, Bergui L, D'Arena G, Bonello L, Horenstein AL, Brennan P, Pepper C, Gaidano G, Malavasi F, Deaglio S. Vaisitti T, et al. Among authors: pepper c. Leukemia. 2010 May;24(5):958-69. doi: 10.1038/leu.2010.36. Epub 2010 Mar 11. Leukemia. 2010. PMID: 20220774

2

Bryostatin induces protein kinase C modulation, Mcl-1 up-regulation and phosphorylation of Bcl-2 resulting in cellular differentiation and resistance to drug-induced apoptosis in B-cell chronic lymphocytic leukemia cells.

Thomas A, Pepper C, Hoy T, Bentley P. Thomas A, et al. Among authors: pepper c. Leuk Lymphoma. 2004 May;45(5):997-1008. doi: 10.1080/10428190310001639470. Leuk Lymphoma. 2004. PMID: 15291360

3

CD38+ chronic lymphocytic leukaemia cells co-express high levels of ZAP-70 and are functionally distinct from their CD38- counter-parts.

Pepper C, Brennan P, Alghazal S, Ward R, Pratt G, Starczynski J, Lin T, Rowntree C, Fegan C. Pepper C, et al. Leukemia. 2006 Apr;20(4):743-4. doi: 10.1038/sj.leu.2404133. Leukemia. 2006. PMID: 16452999 No abstract available.

4

The role of the bax gene polymorphism G(-248)A in chronic lymphocytic leukemia.

Fegan C, Starczynski J, Pratt G, Pepper C. Fegan C, et al. Among authors: pepper c. Leukemia. 2006 Aug;20(8):1460-1. doi: 10.1038/sj.leu.2404280. Epub 2006 Jun 8. Leukemia. 2006. PMID: 16761015 No abstract available.

5

The SDF-1 G > A polymorphism at position 801 plays no role in multiple myeloma but may contribute to an inferior cause-specific survival in chronic lymphocytic leukemia.

Pemberton NC, Paneesha S, Hiller L, Starczynski J, Hooper L, Pepper C, Pratt G, Fegan C. Pemberton NC, et al. Among authors: pepper c. Leuk Lymphoma. 2006 Jul;47(7):1239-44. doi: 10.1080/10428190600562112. Leuk Lymphoma. 2006. PMID: 16923552

6

Highly purified CD38+ and CD38- sub-clones derived from the same chronic lymphocytic leukemia patient have distinct gene expression signatures despite their monoclonal origin.

Pepper C, Ward R, Lin TT, Brennan P, Starczynski J, Musson M, Rowntree C, Bentley P, Mills K, Pratt G, Fegan C. Pepper C, et al. Leukemia. 2007 Apr;21(4):687-96. doi: 10.1038/sj.leu.2404587. Epub 2007 Feb 8. Leukemia. 2007. PMID: 17287849

7

The NF-kappaB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target.

Hewamana S, Alghazal S, Lin TT, Clement M, Jenkins C, Guzman ML, Jordan CT, Neelakantan S, Crooks PA, Burnett AK, Pratt G, Fegan C, Rowntree C, Brennan P, Pepper C. Hewamana S, et al. Among authors: pepper c. Blood. 2008 May 1;111(9):4681-9. doi: 10.1182/blood-2007-11-125278. Epub 2008 Jan 28. Blood. 2008. PMID: 18227347 Free article.

8

Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers.

Pepper C, Lin TT, Pratt G, Hewamana S, Brennan P, Hiller L, Hills R, Ward R, Starczynski J, Austen B, Hooper L, Stankovic T, Fegan C. Pepper C, et al. Blood. 2008 Nov 1;112(9):3807-17. doi: 10.1182/blood-2008-05-157131. Epub 2008 Jul 3. Blood. 2008. PMID: 18599795 Free article.

9

The novel nuclear factor-kappaB inhibitor LC-1 is equipotent in poor prognostic subsets of chronic lymphocytic leukemia and shows strong synergy with fludarabine.

Hewamana S, Lin TT, Jenkins C, Burnett AK, Jordan CT, Fegan C, Brennan P, Rowntree C, Pepper C. Hewamana S, et al. Among authors: pepper c. Clin Cancer Res. 2008 Dec 15;14(24):8102-11. doi: 10.1158/1078-0432.CCR-08-1673. Clin Cancer Res. 2008. PMID: 19088025

10

Rel a is an independent biomarker of clinical outcome in chronic lymphocytic leukemia.

Hewamana S, Lin TT, Rowntree C, Karunanithi K, Pratt G, Hills R, Fegan C, Brennan P, Pepper C. Hewamana S, et al. Among authors: pepper c. J Clin Oncol. 2009 Feb 10;27(5):763-9. doi: 10.1200/JCO.2008.19.1114. Epub 2009 Jan 5. J Clin Oncol. 2009. PMID: 19124804

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