Decreased activity of the heparan sulfate-modifying enzyme glucosaminyl N-deacetylase in hepatocytes from streptozotocin-diabetic rats.
Unger E, Pettersson I, Eriksson UJ, Lindahl U, Kjellén L.
Unger E, et al. Among authors: kjellen l.
J Biol Chem. 1991 May 15;266(14):8671-4.
J Biol Chem. 1991.
PMID: 2026583
Free article.
It has previously been shown that the sulfation of liver heparan sulfate is lowered in diabetes (Kjellen, L., Bielefeld, D., and Hook, M. (1983) Diabetes 32, 337-342). To investigate whether the reduced sulfation is the result of a lowered N-deacetylase activity, we …
It has previously been shown that the sulfation of liver heparan sulfate is lowered in diabetes (Kjellen, L., Bielefeld, D., a …