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Activation of gp130 transduces hypertrophic signal through interaction of scaffolding/docking protein Gab1 with tyrosine phosphatase SHP2 in cardiomyocytes.
Nakaoka Y, Nishida K, Fujio Y, Izumi M, Terai K, Oshima Y, Sugiyama S, Matsuda S, Koyasu S, Yamauchi-Takihara K, Hirano T, Kawase I, Hirota H. Nakaoka Y, et al. Among authors: hirano t. Circ Res. 2003 Aug 8;93(3):221-9. doi: 10.1161/01.RES.0000085562.48906.4A. Epub 2003 Jul 10. Circ Res. 2003. PMID: 12855672
Interaction of scaffolding adaptor protein Gab1 with tyrosine phosphatase SHP2 negatively regulates IGF-I-dependent myogenic differentiation via the ERK1/2 signaling pathway.
Koyama T, Nakaoka Y, Fujio Y, Hirota H, Nishida K, Sugiyama S, Okamoto K, Yamauchi-Takihara K, Yoshimura M, Mochizuki S, Hori M, Hirano T, Mochizuki N. Koyama T, et al. Among authors: hirano t. J Biol Chem. 2008 Aug 29;283(35):24234-44. doi: 10.1074/jbc.M803907200. Epub 2008 Jun 23. J Biol Chem. 2008. PMID: 18577518 Free PMC article.
Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling.
Nakaoka Y, Nishida K, Narimatsu M, Kamiya A, Minami T, Sawa H, Okawa K, Fujio Y, Koyama T, Maeda M, Sone M, Yamasaki S, Arai Y, Koh GY, Kodama T, Hirota H, Otsu K, Hirano T, Mochizuki N. Nakaoka Y, et al. Among authors: hirano t. J Clin Invest. 2007 Jul;117(7):1771-81. doi: 10.1172/JCI30651. J Clin Invest. 2007. PMID: 17571162 Free PMC article.
Docking protein Gab1 is an essential component of postnatal angiogenesis after ischemia via HGF/c-met signaling.
Shioyama W, Nakaoka Y, Higuchi K, Minami T, Taniyama Y, Nishida K, Kidoya H, Sonobe T, Naito H, Arita Y, Hashimoto T, Kuroda T, Fujio Y, Shirai M, Takakura N, Morishita R, Yamauchi-Takihara K, Kodama T, Hirano T, Mochizuki N, Komuro I. Shioyama W, et al. Among authors: hirano t. Circ Res. 2011 Mar 18;108(6):664-75. doi: 10.1161/CIRCRESAHA.110.232223. Epub 2011 Feb 3. Circ Res. 2011. PMID: 21293003
4,273 results