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302 results

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Page 1
Protection of photoreceptors in a mouse model of RP10.
Tam LC, Kiang AS, Chadderton N, Kenna PF, Campbell M, Humphries MM, Farrar GJ, Humphries P. Tam LC, et al. Among authors: humphries p, humphries mm. Adv Exp Med Biol. 2010;664:559-65. doi: 10.1007/978-1-4419-1399-9_64. Adv Exp Med Biol. 2010. PMID: 20238059
Identification of an IMPDH1 mutation in autosomal dominant retinitis pigmentosa (RP10) revealed following comparative microarray analysis of transcripts derived from retinas of wild-type and Rho(-/-) mice.
Kennan A, Aherne A, Palfi A, Humphries M, McKee A, Stitt A, Simpson DA, Demtroder K, Orntoft T, Ayuso C, Kenna PF, Farrar GJ, Humphries P. Kennan A, et al. Among authors: humphries m, humphries p. Hum Mol Genet. 2002 Mar 1;11(5):547-57. doi: 10.1093/hmg/11.5.547. Hum Mol Genet. 2002. PMID: 11875049
On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa.
Aherne A, Kennan A, Kenna PF, McNally N, Lloyd DG, Alberts IL, Kiang AS, Humphries MM, Ayuso C, Engel PC, Gu JJ, Mitchell BS, Farrar GJ, Humphries P. Aherne A, et al. Among authors: humphries p, humphries mm. Hum Mol Genet. 2004 Mar 15;13(6):641-50. doi: 10.1093/hmg/ddh061. Hum Mol Genet. 2004. PMID: 14981049
On the role of IMPDH1 in retinal degeneration.
Kennan A, Aherne A, Bowne SJ, Daiger SP, Farrar GJ, Kenna PF, Humphries P. Kennan A, et al. Among authors: humphries p. Adv Exp Med Biol. 2003;533:13-8. doi: 10.1007/978-1-4615-0067-4_2. Adv Exp Med Biol. 2003. PMID: 15180242 Free PMC article. No abstract available.
RNA interference-mediated suppression and replacement of human rhodopsin in vivo.
O'Reilly M, Palfi A, Chadderton N, Millington-Ward S, Ader M, Cronin T, Tuohy T, Auricchio A, Hildinger M, Tivnan A, McNally N, Humphries MM, Kiang AS, Humphries P, Kenna PF, Farrar GJ. O'Reilly M, et al. Among authors: humphries p, humphries mm. Am J Hum Genet. 2007 Jul;81(1):127-35. doi: 10.1086/519025. Epub 2007 May 23. Am J Hum Genet. 2007. PMID: 17564969 Free PMC article.
Therapeutic benefit derived from RNAi-mediated ablation of IMPDH1 transcripts in a murine model of autosomal dominant retinitis pigmentosa (RP10).
Tam LC, Kiang AS, Kennan A, Kenna PF, Chadderton N, Ader M, Palfi A, Aherne A, Ayuso C, Campbell M, Reynolds A, McKee A, Humphries MM, Farrar GJ, Humphries P. Tam LC, et al. Among authors: humphries p, humphries mm. Hum Mol Genet. 2008 Jul 15;17(14):2084-100. doi: 10.1093/hmg/ddn107. Epub 2008 Apr 1. Hum Mol Genet. 2008. PMID: 18385099
302 results