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Compartmentalized MHC class I antigen processing enhances immunosurveillance by circumventing the law of mass action.
Lev A, Princiotta MF, Zanker D, Takeda K, Gibbs JS, Kumagai C, Waffarn E, Dolan BP, Burgevin A, Van Endert P, Chen W, Bennink JR, Yewdell JW. Lev A, et al. Among authors: chen w. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6964-9. doi: 10.1073/pnas.0910997107. Epub 2010 Mar 29. Proc Natl Acad Sci U S A. 2010. PMID: 20351281 Free PMC article.
Varied Role of Ubiquitylation in Generating MHC Class I Peptide Ligands.
Wei J, Zanker D, Di Carluccio AR, Smelkinson MG, Takeda K, Seedhom MO, Dersh D, Gibbs JS, Yang N, Jadhav A, Chen W, Yewdell JW. Wei J, et al. Among authors: chen w. J Immunol. 2017 May 15;198(10):3835-3845. doi: 10.4049/jimmunol.1602122. Epub 2017 Mar 31. J Immunol. 2017. PMID: 28363906 Free PMC article.
Cells adapted to the proteasome inhibitor 4-hydroxy- 5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone require enzymatically active proteasomes for continued survival.
Princiotta MF, Schubert U, Chen W, Bennink JR, Myung J, Crews CM, Yewdell JW. Princiotta MF, et al. Among authors: chen w. Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):513-8. doi: 10.1073/pnas.98.2.513. Epub 2001 Jan 9. Proc Natl Acad Sci U S A. 2001. PMID: 11149939 Free PMC article.
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