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Page 1
Discovery of novel and potent leukotriene B4 receptor antagonists. Part 1.
Goodnow RA Jr, Hicks A, Sidduri A, Kowalczyk A, Dominique R, Qiao Q, Lou JP, Gillespie P, Fotouhi N, Tilley J, Cohen N, Choudhry S, Cavallo G, Tannu SA, Ventre JD, Lavelle D, Tare NS, Oh H, Lamb M, Kurylko G, Hamid R, Wright MB, Pamidimukkala A, Egan T, Gubler U, Hoffman AF, Wei X, Li YL, O'Neil J, Marcano R, Pozzani K, Molinaro T, Santiago J, Singer L, Hargaden M, Moore D, Catala AR, Chao LC, Hermann G, Venkat R, Mancebo H, Renzetti LM. Goodnow RA Jr, et al. Among authors: sidduri a. J Med Chem. 2010 May 13;53(9):3502-16. doi: 10.1021/jm1001919. J Med Chem. 2010. PMID: 20380377
The discovery of VLA-4 antagonists.
Tilley JW, Chen L, Sidduri A, Fotouhi N. Tilley JW, et al. Among authors: sidduri a. Curr Top Med Chem. 2004;4(14):1509-23. doi: 10.2174/1568026043387502. Curr Top Med Chem. 2004. PMID: 15544541 Review.
Effects of LTB4 receptor antagonism on pulmonary inflammation in rodents and non-human primates.
Hicks A, Goodnow R Jr, Cavallo G, Tannu SA, Ventre JD, Lavelle D, Lora JM, Satjawatcharaphong J, Brovarney M, Dabbagh K, Tare NS, Oh H, Lamb M, Sidduri A, Dominique R, Qiao Q, Lou JP, Gillespie P, Fotouhi N, Kowalczyk A, Kurylko G, Hamid R, Wright MB, Pamidimukkala A, Egan T, Gubler U, Hoffman AF, Wei X, Li YL, O'Neil J, Marcano R, Pozzani K, Molinaro T, Santiago J, Singer L, Hargaden M, Moore D, Catala AR, Chao LC, Benson J, March T, Venkat R, Mancebo H, Renzetti LM. Hicks A, et al. Among authors: sidduri a. Prostaglandins Other Lipid Mediat. 2010 Jun;92(1-4):33-43. doi: 10.1016/j.prostaglandins.2010.02.003. Epub 2010 Mar 7. Prostaglandins Other Lipid Mediat. 2010. PMID: 20214997
Identification of N-acyl 4-(3-pyridonyl)phenylalanine derivatives and their orally active prodrug esters as dual acting α4β1 and α4β7 receptor antagonists.
Tilley JW, Sidduri A, Lou J, Kaplan G, Tare N, Cavallo G, Frank K, Pamidimukkala A, Choi DS, Gerber L, Railkar A, Renzetti L. Tilley JW, et al. Among authors: sidduri a. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1036-40. doi: 10.1016/j.bmcl.2012.12.019. Epub 2012 Dec 20. Bioorg Med Chem Lett. 2013. PMID: 23312471
Identification of N-acyl 4-(5-pyrimidine-2,4-dionyl)phenylalanine derivatives and their orally active prodrug esters as dual-acting alpha4-beta1 and alpha4-beta7 receptor antagonists.
Sidduri A, Tilley JW, Lou J, Tare N, Cavallo G, Frank K, Pamidimukkala A, Choi DS, Gerber L, Railkar A, Renzetti L. Sidduri A, et al. Bioorg Med Chem Lett. 2013 Feb 15;23(4):1026-31. doi: 10.1016/j.bmcl.2012.12.026. Epub 2012 Dec 20. Bioorg Med Chem Lett. 2013. PMID: 23312474
N-Cycloalkanoyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists.
Sidduri A, Tilley JW, Hull K, Lou JP, Kaplan G, Sheffron A, Chen L, Campbell R, Guthrie R, Huang TN, Huby N, Rowan K, Schwinge V, Renzetti LM. Sidduri A, et al. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2475-8. doi: 10.1016/s0960-894x(02)00386-4. Bioorg Med Chem Lett. 2002. PMID: 12161161
N-Aroyl-L-phenylalanine derivatives as VCAM/VLA-4 antagonists.
Sidduri A, Tilley JW, Lou JP, Chen L, Kaplan G, Mennona F, Campbell R, Guthrie R, Huang TN, Rowan K, Schwinge V, Renzetti LM. Sidduri A, et al. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2479-82. doi: 10.1016/s0960-894x(02)00387-6. Bioorg Med Chem Lett. 2002. PMID: 12161162
Discovery of highly selective and orally active lysophosphatidic acid receptor-1 antagonists with potent activity on human lung fibroblasts.
Qian Y, Hamilton M, Sidduri A, Gabriel S, Ren Y, Peng R, Kondru R, Narayanan A, Truitt T, Hamid R, Chen Y, Zhang L, Fretland AJ, Sanchez RA, Chang KC, Lucas M, Schoenfeld RC, Laine D, Fuentes ME, Stevenson CS, Budd DC. Qian Y, et al. Among authors: sidduri a. J Med Chem. 2012 Sep 13;55(17):7920-39. doi: 10.1021/jm301022v. Epub 2012 Aug 29. J Med Chem. 2012. PMID: 22894757
Synthesis and activity of quinolinyl-methylene-thiazolinones as potent and selective cyclin-dependent kinase 1 inhibitors.
Chen S, Chen L, Le NT, Zhao C, Sidduri A, Lou JP, Michoud C, Portland L, Jackson N, Liu JJ, Konzelmann F, Chi F, Tovar C, Xiang Q, Chen Y, Wen Y, Vassilev LT. Chen S, et al. Among authors: sidduri a. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2134-8. doi: 10.1016/j.bmcl.2007.01.081. Epub 2007 Jan 31. Bioorg Med Chem Lett. 2007. PMID: 17303421
12 results