Morcillo EJ - Search Results

1

The preclinical pharmacology of roflumilast--a selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease.

Hatzelmann A, Morcillo EJ, Lungarella G, Adnot S, Sanjar S, Beume R, Schudt C, Tenor H. Hatzelmann A, et al. Among authors: morcillo ej. Pulm Pharmacol Ther. 2010 Aug;23(4):235-56. doi: 10.1016/j.pupt.2010.03.011. Epub 2010 Apr 7. Pulm Pharmacol Ther. 2010. PMID: 20381629 Review.

2

Roflumilast inhibits leukocyte-endothelial cell interactions, expression of adhesion molecules and microvascular permeability.

Sanz MJ, Cortijo J, Taha MA, Cerdá-Nicolás M, Schatton E, Burgbacher B, Klar J, Tenor H, Schudt C, Issekutz AC, Hatzelmann A, Morcillo EJ. Sanz MJ, et al. Among authors: morcillo ej. Br J Pharmacol. 2007 Oct;152(4):481-92. doi: 10.1038/sj.bjp.0707428. Epub 2007 Aug 20. Br J Pharmacol. 2007. PMID: 17704822 Free PMC article.

3

Roflumilast, a phosphodiesterase 4 inhibitor, alleviates bleomycin-induced lung injury.

Cortijo J, Iranzo A, Milara X, Mata M, Cerdá-Nicolás M, Ruiz-Saurí A, Tenor H, Hatzelmann A, Morcillo EJ. Cortijo J, et al. Among authors: morcillo ej. Br J Pharmacol. 2009 Feb;156(3):534-44. doi: 10.1111/j.1476-5381.2008.00041.x. Br J Pharmacol. 2009. PMID: 19154443 Free PMC article.

4

PDE4 inhibitors as new anti-inflammatory drugs: effects on cell trafficking and cell adhesion molecules expression.

Sanz MJ, Cortijo J, Morcillo EJ. Sanz MJ, et al. Among authors: morcillo ej. Pharmacol Ther. 2005 Jun;106(3):269-97. doi: 10.1016/j.pharmthera.2004.12.001. Epub 2005 Feb 25. Pharmacol Ther. 2005. PMID: 15922015 Review.

5

Direct effect of cigarette smoke on human pulmonary artery tension.

Ortiz JL, Milara J, Juan G, Montesinos JL, Mata M, Ramón M, Morcillo E, Cortijo J. Ortiz JL, et al. Pulm Pharmacol Ther. 2010 Jun;23(3):222-8. doi: 10.1016/j.pupt.2009.11.001. Epub 2009 Nov 25. Pulm Pharmacol Ther. 2010. PMID: 19931631

6

Roflumilast Prevents the Metabolic Effects of Bleomycin-Induced Fibrosis in a Murine Model.

Milara J, Morcillo E, Monleon D, Tenor H, Cortijo J. Milara J, et al. PLoS One. 2015 Jul 20;10(7):e0133453. doi: 10.1371/journal.pone.0133453. eCollection 2015. PLoS One. 2015. PMID: 26192616 Free PMC article.

7

Non-neuronal cholinergic system contributes to corticosteroid resistance in chronic obstructive pulmonary disease patients.

Milara J, Cervera A, de Diego A, Sanz C, Juan G, Gavaldà A, Miralpeix M, Morcillo E, Cortijo J. Milara J, et al. Respir Res. 2016 Nov 8;17(1):145. doi: 10.1186/s12931-016-0467-8. Respir Res. 2016. PMID: 27825347 Free PMC article.

8

Erythromycin exerts in vivo anti-inflammatory activity downregulating cell adhesion molecule expression.

Sanz MJ, Nabah YN, Cerdá-Nicolás M, O'Connor JE, Issekutz AC, Cortijo J, Morcillo EJ. Sanz MJ, et al. Among authors: morcillo ej. Br J Pharmacol. 2005 Jan;144(2):190-201. doi: 10.1038/sj.bjp.0706021. Br J Pharmacol. 2005. PMID: 15665859 Free PMC article.

9

Roflumilast improves corticosteroid resistance COPD bronchial epithelial cells stimulated with toll like receptor 3 agonist.

Milara J, Morell A, Ballester B, Sanz C, Freire J, Qian X, Alonso-Garcia M, Morcillo E, Cortijo J. Milara J, et al. Respir Res. 2015 Feb 5;16(1):12. doi: 10.1186/s12931-015-0179-5. Respir Res. 2015. PMID: 25652132 Free PMC article.

10

Selective Inhibition of Phosphodiesterases 4A, B, C and D Isoforms in Chronic Respiratory Diseases: Current and Future Evidences.

Contreras S, Milara J, Morcillo E, Cortijo J. Contreras S, et al. Curr Pharm Des. 2017;23(14):2073-2083. doi: 10.2174/1381612823666170214105651. Curr Pharm Des. 2017. PMID: 28201975 Review.

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