Antunes AM - Search Results

1

Amino acid adduct formation by the nevirapine metabolite, 12-hydroxynevirapine--a possible factor in nevirapine toxicity.

Antunes AM, Godinho AL, Martins IL, Justino GC, Beland FA, Marques MM. Antunes AM, et al. Chem Res Toxicol. 2010 May 17;23(5):888-99. doi: 10.1021/tx900443z. Chem Res Toxicol. 2010. PMID: 20392079

2

Synthesis and characterization of DNA adducts from the HIV reverse transcriptase inhibitor nevirapine.

Antunes AM, Duarte MP, Santos PP, Gamboa da Costa G, Heinze TM, Beland FA, Marques MM. Antunes AM, et al. Chem Res Toxicol. 2008 Jul;21(7):1443-56. doi: 10.1021/tx8000972. Epub 2008 Jul 3. Chem Res Toxicol. 2008. PMID: 18597499

3

Protein adducts as prospective biomarkers of nevirapine toxicity.

Antunes AM, Godinho AL, Martins IL, Oliveira MC, Gomes RA, Coelho AV, Beland FA, Marques MM. Antunes AM, et al. Chem Res Toxicol. 2010 Nov 15;23(11):1714-25. doi: 10.1021/tx100186t. Epub 2010 Sep 1. Chem Res Toxicol. 2010. PMID: 20809596 Free PMC article.

4

Synthesis and oxidation of 2-hydroxynevirapine, a metabolite of the HIV reverse transcriptase inhibitor nevirapine.

Antunes AM, Novais DA, da Silva JL, Santos PP, Oliveira MC, Beland FA, Marques MM. Antunes AM, et al. Org Biomol Chem. 2011 Oct 26;9(22):7822-35. doi: 10.1039/c1ob06052j. Epub 2011 Oct 3. Org Biomol Chem. 2011. PMID: 21969039

5

Reactive aldehyde metabolites from the anti-HIV drug abacavir: amino acid adducts as possible factors in abacavir toxicity.

Charneira C, Godinho AL, Oliveira MC, Pereira SA, Monteiro EC, Marques MM, Antunes AM. Charneira C, et al. Among authors: antunes am. Chem Res Toxicol. 2011 Dec 19;24(12):2129-41. doi: 10.1021/tx200337b. Epub 2011 Nov 11. Chem Res Toxicol. 2011. PMID: 22032494

6

Oxidation of 2-hydroxynevirapine, a phenolic metabolite of the anti-HIV drug nevirapine: evidence for an unusual pyridine ring contraction.

Antunes AM, Sidarus M, Novais DA, Harjivan SG, Santos PP, Ferreira da Silva JL, Beland FA, Marques MM. Antunes AM, et al. Molecules. 2012 Mar 5;17(3):2616-27. doi: 10.3390/molecules17032616. Molecules. 2012. PMID: 22391597 Free PMC article.

7

Biomimetic oxidation of aromatic xenobiotics: synthesis of the phenolic metabolites from the anti-HIV drug efavirenz.

Wanke R, Novais DA, Harjivan SG, Marques MM, Antunes AM. Wanke R, et al. Among authors: antunes am. Org Biomol Chem. 2012 Jun 21;10(23):4554-61. doi: 10.1039/c2ob25212k. Epub 2012 May 8. Org Biomol Chem. 2012. PMID: 22569890

8

Evidence for nevirapine bioactivation in man: searching for the first step in the mechanism of nevirapine toxicity.

Caixas U, Antunes AM, Marinho AT, Godinho AL, Grilo NM, Marques MM, Oliveira MC, Branco T, Monteiro EC, Pereira SA. Caixas U, et al. Among authors: antunes am. Toxicology. 2012 Nov 15;301(1-3):33-9. doi: 10.1016/j.tox.2012.06.013. Epub 2012 Jun 28. Toxicology. 2012. PMID: 22750752 Clinical Trial.

9

Monitoring abacavir bioactivation in humans: screening for an aldehyde metabolite.

Grilo NM, Antunes AM, Caixas U, Marinho AT, Charneira C, Conceição Oliveira M, Monteiro EC, Matilde Marques M, Pereira SA. Grilo NM, et al. Among authors: antunes am. Toxicol Lett. 2013 May 10;219(1):59-64. doi: 10.1016/j.toxlet.2013.02.021. Epub 2013 Mar 4. Toxicol Lett. 2013. PMID: 23467017 Free article. Clinical Trial.

10

2'-Deoxythymidine adducts from the anti-HIV drug nevirapine.

Antunes AM, Wolf B, Oliveira MC, Beland FA, Marques MM. Antunes AM, et al. Molecules. 2013 Apr 26;18(5):4955-71. doi: 10.3390/molecules18054955. Molecules. 2013. PMID: 23624649 Free PMC article.

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