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Page 1
Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma.
Noushmehr H, Weisenberger DJ, Diefes K, Phillips HS, Pujara K, Berman BP, Pan F, Pelloski CE, Sulman EP, Bhat KP, Verhaak RG, Hoadley KA, Hayes DN, Perou CM, Schmidt HK, Ding L, Wilson RK, Van Den Berg D, Shen H, Bengtsson H, Neuvial P, Cope LM, Buckley J, Herman JG, Baylin SB, Laird PW, Aldape K; Cancer Genome Atlas Research Network. Noushmehr H, et al. Among authors: diefes k. Cancer Cell. 2010 May 18;17(5):510-22. doi: 10.1016/j.ccr.2010.03.017. Epub 2010 Apr 15. Cancer Cell. 2010. PMID: 20399149 Free PMC article.
The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma.
Bhat KP, Salazar KL, Balasubramaniyan V, Wani K, Heathcock L, Hollingsworth F, James JD, Gumin J, Diefes KL, Kim SH, Turski A, Azodi Y, Yang Y, Doucette T, Colman H, Sulman EP, Lang FF, Rao G, Copray S, Vaillant BD, Aldape KD. Bhat KP, et al. Among authors: diefes kl. Genes Dev. 2011 Dec 15;25(24):2594-609. doi: 10.1101/gad.176800.111. Genes Dev. 2011. PMID: 22190458 Free PMC article.
Significance of complete 1p/19q co-deletion, IDH1 mutation and MGMT promoter methylation in gliomas: use with caution.
Boots-Sprenger SH, Sijben A, Rijntjes J, Tops BB, Idema AJ, Rivera AL, Bleeker FE, Gijtenbeek AM, Diefes K, Heathcock L, Aldape KD, Jeuken JW, Wesseling P. Boots-Sprenger SH, et al. Among authors: diefes k. Mod Pathol. 2013 Jul;26(7):922-9. doi: 10.1038/modpathol.2012.166. Epub 2013 Feb 22. Mod Pathol. 2013. PMID: 23429602 Free article.
Interlaboratory comparison of IDH mutation detection.
van den Bent MJ, Hartmann C, Preusser M, Ströbel T, Dubbink HJ, Kros JM, von Deimling A, Boisselier B, Sanson M, Halling KC, Diefes KL, Aldape K, Giannini C. van den Bent MJ, et al. Among authors: diefes kl. J Neurooncol. 2013 Apr;112(2):173-8. doi: 10.1007/s11060-013-1056-z. Epub 2013 Jan 29. J Neurooncol. 2013. PMID: 23358936
Alkylpurine-DNA-N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients.
Agnihotri S, Gajadhar AS, Ternamian C, Gorlia T, Diefes KL, Mischel PS, Kelly J, McGown G, Thorncroft M, Carlson BL, Sarkaria JN, Margison GP, Aldape K, Hawkins C, Hegi M, Guha A. Agnihotri S, et al. Among authors: diefes kl. J Clin Invest. 2012 Jan;122(1):253-66. doi: 10.1172/JCI59334. Epub 2011 Dec 12. J Clin Invest. 2012. PMID: 22156195 Free PMC article.