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Cytotoxic drugs up-regulate epidermal growth factor receptor (EGFR) expression in colon cancer cells and enhance their susceptibility to EGFR-targeted antibody-dependent cell-mediated-cytotoxicity (ADCC).
Correale P, Marra M, Remondo C, Migali C, Misso G, Arcuri FP, Del Vecchio MT, Carducci A, Loiacono L, Tassone P, Abbruzzese A, Tagliaferri P, Caraglia M. Correale P, et al. Among authors: marra m. Eur J Cancer. 2010 Jun;46(9):1703-11. doi: 10.1016/j.ejca.2010.03.005. Eur J Cancer. 2010. PMID: 20399639
Cetuximab ± chemotherapy enhances dendritic cell-mediated phagocytosis of colon cancer cells and ignites a highly efficient colon cancer antigen-specific cytotoxic T-cell response in vitro.
Correale P, Botta C, Cusi MG, Del Vecchio MT, De Santi MM, Gori Savellini G, Bestoso E, Apollinari S, Mannucci S, Marra M, Abbruzzese A, Aquino A, Turriziani M, Bonmassar L, Caraglia M, Tagliaferri P. Correale P, et al. Among authors: marra m. Int J Cancer. 2012 Apr 1;130(7):1577-89. doi: 10.1002/ijc.26181. Epub 2011 Aug 16. Int J Cancer. 2012. PMID: 21618510
Chemotherapy regimen GOLF induces apoptosis in colon cancer cells through multi-chaperone complex inactivation and increased Raf-1 ubiquitin-dependent degradation.
Caraglia M, Marra M, Budillon A, Meo G, Ricciardiello F, Bismuto E, Brachelente G, Francini G, Giordano A, Correale P, Abbruzzese A. Caraglia M, et al. Among authors: marra m. Cancer Biol Ther. 2005 Oct;4(10):1159-67. doi: 10.4161/cbt.4.10.2206. Epub 2005 Oct 23. Cancer Biol Ther. 2005. PMID: 16294035 Free article.
The farnesyltransferase inhibitor R115777 (ZARNESTRA) enhances the pro-apoptotic activity of interferon-alpha through the inhibition of multiple survival pathways.
Caraglia M, Marra M, Viscomi C, D'Alessandro AM, Budillon A, Meo G, Arra C, Barbieri A, Rapp UR, Baldi A, Tassone P, Venuta S, Abbruzzese A, Tagliaferri P. Caraglia M, et al. Among authors: marra m. Int J Cancer. 2007 Nov 15;121(10):2317-30. doi: 10.1002/ijc.22964. Int J Cancer. 2007. PMID: 17657738
Tumour-specific uptake of anti-cancer drugs: the future is here.
Caraglia M, Marra M, Misso G, Lamberti M, Salzano G, De Rosa G, Abbruzzese A. Caraglia M, et al. Among authors: marra m. Curr Drug Metab. 2012 Jan;13(1):4-21. doi: 10.2174/138920012798356871. Curr Drug Metab. 2012. PMID: 22292808 Review.
Alpha-interferon and its effects on signalling pathways within cells.
Caraglia M, Vitale G, Marra M, Budillon A, Tagliaferri P, Abbruzzese A. Caraglia M, et al. Among authors: marra m. Curr Protein Pept Sci. 2004 Dec;5(6):475-85. doi: 10.2174/1389203043379378. Curr Protein Pept Sci. 2004. PMID: 15581417 Review.
1,248 results