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A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly.
Ho AJ, Stein JL, Hua X, Lee S, Hibar DP, Leow AD, Dinov ID, Toga AW, Saykin AJ, Shen L, Foroud T, Pankratz N, Huentelman MJ, Craig DW, Gerber JD, Allen AN, Corneveaux JJ, Stephan DA, DeCarli CS, DeChairo BM, Potkin SG, Jack CR Jr, Weiner MW, Raji CA, Lopez OL, Becker JT, Carmichael OT, Thompson PM; Alzheimer's Disease Neuroimaging Initiative. Ho AJ, et al. Among authors: hibar dp. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8404-9. doi: 10.1073/pnas.0910878107. Epub 2010 Apr 19. Proc Natl Acad Sci U S A. 2010. PMID: 20404173 Free PMC article.
Mapping Alzheimer's disease progression in 1309 MRI scans: power estimates for different inter-scan intervals.
Hua X, Lee S, Hibar DP, Yanovsky I, Leow AD, Toga AW, Jack CR Jr, Bernstein MA, Reiman EM, Harvey DJ, Kornak J, Schuff N, Alexander GE, Weiner MW, Thompson PM; Alzheimer's Disease Neuroimaging Initiative. Hua X, et al. Among authors: hibar dp. Neuroimage. 2010 May 15;51(1):63-75. doi: 10.1016/j.neuroimage.2010.01.104. Epub 2010 Feb 6. Neuroimage. 2010. PMID: 20139010 Free PMC article.
Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease.
Stein JL, Hua X, Morra JH, Lee S, Hibar DP, Ho AJ, Leow AD, Toga AW, Sul JH, Kang HM, Eskin E, Saykin AJ, Shen L, Foroud T, Pankratz N, Huentelman MJ, Craig DW, Gerber JD, Allen AN, Corneveaux JJ, Stephan DA, Webster J, DeChairo BM, Potkin SG, Jack CR Jr, Weiner MW, Thompson PM; Alzheimer's Disease Neuroimaging Initiative. Stein JL, et al. Among authors: hibar dp. Neuroimage. 2010 Jun;51(2):542-54. doi: 10.1016/j.neuroimage.2010.02.068. Epub 2010 Mar 1. Neuroimage. 2010. PMID: 20197096 Free PMC article.
Boosting power for clinical trials using classifiers based on multiple biomarkers.
Kohannim O, Hua X, Hibar DP, Lee S, Chou YY, Toga AW, Jack CR Jr, Weiner MW, Thompson PM; Alzheimer's Disease Neuroimaging Initiative. Kohannim O, et al. Among authors: hibar dp. Neurobiol Aging. 2010 Aug;31(8):1429-42. doi: 10.1016/j.neurobiolaging.2010.04.022. Epub 2010 Jun 11. Neurobiol Aging. 2010. PMID: 20541286 Free PMC article. Clinical Trial.
Obesity is linked with lower brain volume in 700 AD and MCI patients.
Ho AJ, Raji CA, Becker JT, Lopez OL, Kuller LH, Hua X, Lee S, Hibar D, Dinov ID, Stein JL, Jack CR Jr, Weiner MW, Toga AW, Thompson PM; Cardiovascular Health Study; ADNI. Ho AJ, et al. Neurobiol Aging. 2010 Aug;31(8):1326-39. doi: 10.1016/j.neurobiolaging.2010.04.006. Epub 2010 Jun 8. Neurobiol Aging. 2010. PMID: 20570405 Free PMC article.
Sex and age differences in atrophic rates: an ADNI study with n=1368 MRI scans.
Hua X, Hibar DP, Lee S, Toga AW, Jack CR Jr, Weiner MW, Thompson PM; Alzheimer's Disease Neuroimaging Initiative. Hua X, et al. Among authors: hibar dp. Neurobiol Aging. 2010 Aug;31(8):1463-80. doi: 10.1016/j.neurobiolaging.2010.04.033. Neurobiol Aging. 2010. PMID: 20620666 Free PMC article.
Voxelwise gene-wide association study (vGeneWAS): multivariate gene-based association testing in 731 elderly subjects.
Hibar DP, Stein JL, Kohannim O, Jahanshad N, Saykin AJ, Shen L, Kim S, Pankratz N, Foroud T, Huentelman MJ, Potkin SG, Jack CR Jr, Weiner MW, Toga AW, Thompson PM; Alzheimer's Disease Neuroimaging Initiative. Hibar DP, et al. Neuroimage. 2011 Jun 15;56(4):1875-91. doi: 10.1016/j.neuroimage.2011.03.077. Epub 2011 Apr 8. Neuroimage. 2011. PMID: 21497199 Free PMC article.
Discovery and replication of dopamine-related gene effects on caudate volume in young and elderly populations (N=1198) using genome-wide search.
Stein JL, Hibar DP, Madsen SK, Khamis M, McMahon KL, de Zubicaray GI, Hansell NK, Montgomery GW, Martin NG, Wright MJ, Saykin AJ, Jack CR Jr, Weiner MW, Toga AW, Thompson PM; Alzheimer’s Disease Neuroimaging Initiative Investigators. Stein JL, et al. Among authors: hibar dp. Mol Psychiatry. 2011 Sep;16(9):927-37, 881. doi: 10.1038/mp.2011.32. Epub 2011 Apr 19. Mol Psychiatry. 2011. PMID: 21502949 Free PMC article.
Hippocampal volume is related to body mass index in Alzheimer's disease.
Ho AJ, Raji CA, Saharan P, DeGiorgio A, Madsen SK, Hibar DP, Stein JL, Becker JT, Lopez OL, Toga AW, Thompson PM; Alzheimer's Disease Neuroimaging Initiative. Ho AJ, et al. Among authors: hibar dp. Neuroreport. 2011 Jan 5;22(1):10-4. doi: 10.1097/wnr.0b013e3283412868. Neuroreport. 2011. PMID: 21539003 Free PMC article.
120 results