Jameson GB - Search Results

1

Specificity and mutational analysis of the metal-dependent 3-deoxy-D-manno-octulosonate 8-phosphate synthase from Acidithiobacillus ferrooxidans.

Allison TM, Yeoman JA, Hutton RD, Cochrane FC, Jameson GB, Parker EJ. Allison TM, et al. Among authors: jameson gb. Biochim Biophys Acta. 2010 Jul;1804(7):1526-36. doi: 10.1016/j.bbapap.2010.04.005. Epub 2010 Apr 18. Biochim Biophys Acta. 2010. PMID: 20406700

2

Reversing evolution: re-establishing obligate metal ion dependence in a metal-independent KDO8P synthase.

Cochrane FC, Cookson TV, Jameson GB, Parker EJ. Cochrane FC, et al. Among authors: jameson gb. J Mol Biol. 2009 Jul 24;390(4):646-61. doi: 10.1016/j.jmb.2009.05.014. Epub 2009 May 15. J Mol Biol. 2009. PMID: 19447118

3

Targeting the role of a key conserved motif for substrate selection and catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase.

Allison TM, Hutton RD, Cochrane FC, Yeoman JA, Jameson GB, Parker EJ. Allison TM, et al. Among authors: jameson gb. Biochemistry. 2011 May 10;50(18):3686-95. doi: 10.1021/bi200251f. Epub 2011 Apr 18. Biochemistry. 2011. PMID: 21438567

4

An extended β7α7 substrate-binding loop is essential for efficient catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase.

Allison TM, Hutton RD, Jiao W, Gloyne BJ, Nimmo EB, Jameson GB, Parker EJ. Allison TM, et al. Among authors: jameson gb. Biochemistry. 2011 Nov 1;50(43):9318-27. doi: 10.1021/bi201231e. Epub 2011 Oct 10. Biochemistry. 2011. PMID: 21942786

5

Examining the role of intersubunit contacts in catalysis by 3-deoxy-d-manno-octulosonate 8-phosphate synthase.

Allison TM, Cochrane FC, Jameson GB, Parker EJ. Allison TM, et al. Among authors: jameson gb. Biochemistry. 2013 Jul 9;52(27):4676-86. doi: 10.1021/bi400521f. Epub 2013 Jun 26. Biochemistry. 2013. PMID: 23746359

6

Substrate ambiguity and crystal structure of Pyrococcus furiosus 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase: an ancestral 3-deoxyald-2-ulosonate-phosphate synthase?

Schofield LR, Anderson BF, Patchett ML, Norris GE, Jameson GB, Parker EJ. Schofield LR, et al. Among authors: jameson gb. Biochemistry. 2005 Sep 13;44(36):11950-62. doi: 10.1021/bi050577z. Biochemistry. 2005. PMID: 16142893

7

Investigating the role of the hydroxyl groups of substrate erythrose 4-phosphate in the reaction catalysed by the first enzyme of the shikimate pathway.

Tran D, Pietersma AL, Schofield LR, Rost M, Jameson GB, Parker EJ. Tran D, et al. Among authors: jameson gb. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6838-41. doi: 10.1016/j.bmcl.2011.09.017. Epub 2011 Sep 16. Bioorg Med Chem Lett. 2011. PMID: 21978677

8

Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery.

Jiao W, Hutton RD, Cross PJ, Jameson GB, Parker EJ. Jiao W, et al. Among authors: jameson gb. J Mol Biol. 2012 Jan 27;415(4):716-26. doi: 10.1016/j.jmb.2011.11.037. Epub 2011 Dec 2. J Mol Biol. 2012. PMID: 22154807

9

Three sites and you are out: ternary synergistic allostery controls aromatic amino acid biosynthesis in Mycobacterium tuberculosis.

Blackmore NJ, Reichau S, Jiao W, Hutton RD, Baker EN, Jameson GB, Parker EJ. Blackmore NJ, et al. Among authors: jameson gb. J Mol Biol. 2013 May 13;425(9):1582-92. doi: 10.1016/j.jmb.2012.12.019. Epub 2012 Dec 28. J Mol Biol. 2013. PMID: 23274137

10

Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain.

Cross PJ, Allison TM, Dobson RC, Jameson GB, Parker EJ. Cross PJ, et al. Among authors: jameson gb. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2111-6. doi: 10.1073/pnas.1217923110. Epub 2013 Jan 23. Proc Natl Acad Sci U S A. 2013. PMID: 23345433 Free PMC article.

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