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Page 1
Dysregulated humoral immunity to nontyphoidal Salmonella in HIV-infected African adults.
MacLennan CA, Gilchrist JJ, Gordon MA, Cunningham AF, Cobbold M, Goodall M, Kingsley RA, van Oosterhout JJ, Msefula CL, Mandala WL, Leyton DL, Marshall JL, Gondwe EN, Bobat S, López-Macías C, Doffinger R, Henderson IR, Zijlstra EE, Dougan G, Drayson MT, MacLennan IC, Molyneux ME. MacLennan CA, et al. Science. 2010 Apr 23;328(5977):508-12. doi: 10.1126/science.1180346. Science. 2010. PMID: 20413503 Free PMC article.
The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1b cell antibody response.
Gil-Cruz C, Bobat S, Marshall JL, Kingsley RA, Ross EA, Henderson IR, Leyton DL, Coughlan RE, Khan M, Jensen KT, Buckley CD, Dougan G, MacLennan IC, López-Macías C, Cunningham AF. Gil-Cruz C, et al. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9803-8. doi: 10.1073/pnas.0812431106. Epub 2009 Jun 1. Proc Natl Acad Sci U S A. 2009. PMID: 19487686 Free PMC article.
IgG Responses to Porins and Lipopolysaccharide within an Outer Membrane-Based Vaccine against Nontyphoidal Salmonella Develop at Discordant Rates.
Schager AE, Dominguez-Medina CC, Necchi F, Micoli F, Goh YS, Goodall M, Flores-Langarica A, Bobat S, Cook CNL, Arcuri M, Marini A, King LDW, Morris FC, Anderson G, Toellner KM, Henderson IR, López-Macías C, MacLennan CA, Cunningham AF. Schager AE, et al. mBio. 2018 Mar 6;9(2):e02379-17. doi: 10.1128/mBio.02379-17. mBio. 2018. PMID: 29511082 Free PMC article.
Soluble flagellin, FliC, induces an Ag-specific Th2 response, yet promotes T-bet-regulated Th1 clearance of Salmonella typhimurium infection.
Bobat S, Flores-Langarica A, Hitchcock J, Marshall JL, Kingsley RA, Goodall M, Gil-Cruz C, Serre K, Leyton DL, Letran SE, Gaspal F, Chester R, Chamberlain JL, Dougan G, López-Macías C, Henderson IR, Alexander J, MacLennan IC, Cunningham AF. Bobat S, et al. Eur J Immunol. 2011 Jun;41(6):1606-18. doi: 10.1002/eji.201041089. Epub 2011 May 10. Eur J Immunol. 2011. PMID: 21469112 Free article.
CD31 is required on CD4+ T cells to promote T cell survival during Salmonella infection.
Ross EA, Coughlan RE, Flores-Langarica A, Bobat S, Marshall JL, Hussain K, Charlesworth J, Abhyankar N, Hitchcock J, Gil C, López-Macías C, Henderson IR, Khan M, Watson SP, MacLennan IC, Buckley CD, Cunningham AF. Ross EA, et al. J Immunol. 2011 Aug 15;187(4):1553-65. doi: 10.4049/jimmunol.1000502. Epub 2011 Jul 6. J Immunol. 2011. PMID: 21734076 Free PMC article.
The capsular polysaccharide Vi from Salmonella typhi is a B1b antigen.
Marshall JL, Flores-Langarica A, Kingsley RA, Hitchcock JR, Ross EA, López-Macías C, Lakey J, Martin LB, Toellner KM, MacLennan CA, MacLennan IC, Henderson IR, Dougan G, Cunningham AF. Marshall JL, et al. J Immunol. 2012 Dec 15;189(12):5527-32. doi: 10.4049/jimmunol.1103166. Epub 2012 Nov 16. J Immunol. 2012. PMID: 23162127 Free PMC article.
Natural and vaccine-mediated immunity to Salmonella Typhimurium is impaired by the helminth Nippostrongylus brasiliensis.
Bobat S, Darby M, Mrdjen D, Cook C, Logan E, Auret J, Jones E, Schnoeller C, Flores-Langarica A, Ross EA, Vira A, López-Macías C, Henderson IR, Alexander J, Brombacher F, Horsnell WG, Cunningham AF. Bobat S, et al. PLoS Negl Trop Dis. 2014 Dec 4;8(12):e3341. doi: 10.1371/journal.pntd.0003341. eCollection 2014 Dec. PLoS Negl Trop Dis. 2014. PMID: 25474738 Free PMC article.
IgG1 Is Required for Optimal Protection after Immunization with the Purified Porin OmpD from Salmonella Typhimurium.
Zhang Y, Dominguez-Medina C, Cumley NJ, Heath JN, Essex SJ, Bobat S, Schager A, Goodall M, Kracker S, Buckley CD, May RC, Kingsley RA, MacLennan CA, López-Macías C, Cunningham AF, Toellner KM. Zhang Y, et al. J Immunol. 2017 Dec 15;199(12):4103-4109. doi: 10.4049/jimmunol.1700952. Epub 2017 Nov 10. J Immunol. 2017. PMID: 29127147 Free PMC article.
Outer membrane protein size and LPS O-antigen define protective antibody targeting to the Salmonella surface.
Domínguez-Medina CC, Pérez-Toledo M, Schager AE, Marshall JL, Cook CN, Bobat S, Hwang H, Chun BJ, Logan E, Bryant JA, Channell WM, Morris FC, Jossi SE, Alshayea A, Rossiter AE, Barrow PA, Horsnell WG, MacLennan CA, Henderson IR, Lakey JH, Gumbart JC, López-Macías C, Bavro VN, Cunningham AF. Domínguez-Medina CC, et al. Nat Commun. 2020 Feb 12;11(1):851. doi: 10.1038/s41467-020-14655-9. Nat Commun. 2020. PMID: 32051408 Free PMC article.
110 results