Rubin E - Search Results

1

Deficiency of the dual ubiquitin/SUMO ligase Topors results in genetic instability and an increased rate of malignancy in mice.

Marshall H, Bhaumik M, Aviv H, Moore D, Yao M, Dutta J, Rahim H, Gounder M, Ganesan S, Saleem A, Rubin E. Marshall H, et al. Among authors: rubin e. BMC Mol Biol. 2010 Apr 29;11:31. doi: 10.1186/1471-2199-11-31. BMC Mol Biol. 2010. PMID: 20429939 Free PMC article.

2

TOPORS functions as a SUMO-1 E3 ligase for chromatin-modifying proteins.

Pungaliya P, Kulkarni D, Park HJ, Marshall H, Zheng H, Lackland H, Saleem A, Rubin EH. Pungaliya P, et al. J Proteome Res. 2007 Oct;6(10):3918-23. doi: 10.1021/pr0703674. Epub 2007 Sep 6. J Proteome Res. 2007. PMID: 17803295

3

Identification of phosphorylation sites of TOPORS and a role for serine 98 in the regulation of ubiquitin but not SUMO E3 ligase activity.

Park HJ, Zheng H, Kulkarni D, Kerrigan J, Pungaliya P, Saleem A, Rubin EH. Park HJ, et al. Biochemistry. 2008 Dec 30;47(52):13887-96. doi: 10.1021/bi801904q. Biochemistry. 2008. PMID: 19053840

4

The topoisomerase I-binding RING protein, topors, is associated with promyelocytic leukemia nuclear bodies.

Rasheed ZA, Saleem A, Ravee Y, Pandolfi PP, Rubin EH. Rasheed ZA, et al. Exp Cell Res. 2002 Jul 15;277(2):152-60. doi: 10.1006/excr.2002.5550. Exp Cell Res. 2002. PMID: 12083797

5

The topoisomerase I- and p53-binding protein topors is differentially expressed in normal and malignant human tissues and may function as a tumor suppressor.

Saleem A, Dutta J, Malegaonkar D, Rasheed F, Rasheed Z, Rajendra R, Marshall H, Luo M, Li H, Rubin EH. Saleem A, et al. Oncogene. 2004 Jul 8;23(31):5293-300. doi: 10.1038/sj.onc.1207700. Oncogene. 2004. PMID: 15107820

6

Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53.

Rajendra R, Malegaonkar D, Pungaliya P, Marshall H, Rasheed Z, Brownell J, Liu LF, Lutzker S, Saleem A, Rubin EH. Rajendra R, et al. J Biol Chem. 2004 Aug 27;279(35):36440-4. doi: 10.1074/jbc.C400300200. Epub 2004 Jul 9. J Biol Chem. 2004. PMID: 15247280 Free article.

7

Transcription-dependent degradation of topoisomerase I-DNA covalent complexes.

Desai SD, Zhang H, Rodriguez-Bauman A, Yang JM, Wu X, Gounder MK, Rubin EH, Liu LF. Desai SD, et al. Mol Cell Biol. 2003 Apr;23(7):2341-50. doi: 10.1128/MCB.23.7.2341-2350.2003. Mol Cell Biol. 2003. PMID: 12640119 Free PMC article.

8

Elevated expression of ISG15 in tumor cells interferes with the ubiquitin/26S proteasome pathway.

Desai SD, Haas AL, Wood LM, Tsai YC, Pestka S, Rubin EH, Saleem A, Nur-E-Kamal A, Liu LF. Desai SD, et al. Among authors: rubin eh. Cancer Res. 2006 Jan 15;66(2):921-8. doi: 10.1158/0008-5472.CAN-05-1123. Cancer Res. 2006. PMID: 16424026

9

Effects of drug efflux proteins and topoisomerase I mutations on the camptothecin analogue gimatecan.

Gounder MK, Nazar AS, Saleem A, Pungaliya P, Kulkarni D, Versace R, Rubin EH. Gounder MK, et al. Invest New Drugs. 2008 Jun;26(3):205-13. doi: 10.1007/s10637-007-9093-0. Epub 2007 Oct 18. Invest New Drugs. 2008. PMID: 17943230

10

Correction: The topoisomerase I- and p53-binding protein topors is differentially expressed in normal and malignant human tissues and may function as a tumor suppressor.

Saleem A, Dutta J, Malegaonkar D, Rasheed F, Rasheed Z, Rajendra R, Marshall H, Luo M, Li H, Rubin EH. Saleem A, et al. Oncogene. 2019 Aug;38(35):6322. doi: 10.1038/s41388-019-0874-7. Oncogene. 2019. PMID: 31296957

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