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Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment.
Bertolini G, Roz L, Perego P, Tortoreto M, Fontanella E, Gatti L, Pratesi G, Fabbri A, Andriani F, Tinelli S, Roz E, Caserini R, Lo Vullo S, Camerini T, Mariani L, Delia D, Calabrò E, Pastorino U, Sozzi G. Bertolini G, et al. Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16281-6. doi: 10.1073/pnas.0905653106. Epub 2009 Sep 10. Proc Natl Acad Sci U S A. 2009. PMID: 19805294 Free PMC article.
The "stem" of chemoresistance.
Bertolini G, Gatti L, Roz L. Bertolini G, et al. Cell Cycle. 2010 Feb 15;9(4):628-9. doi: 10.4161/cc.9.4.10821. Epub 2010 Feb 2. Cell Cycle. 2010. PMID: 20107309 No abstract available.
Evaluation and validation of a robust single cell RNA-amplification protocol through transcriptional profiling of enriched lung cancer initiating cells.
Rothwell DG, Li Y, Ayub M, Tate C, Newton G, Hey Y, Carter L, Faulkner S, Moro M, Pepper S, Miller C, Blackhall F, Bertolini G, Roz L, Dive C, Brady G. Rothwell DG, et al. Among authors: bertolini g. BMC Genomics. 2014 Dec 17;15(1):1129. doi: 10.1186/1471-2164-15-1129. BMC Genomics. 2014. PMID: 25519510 Free PMC article.
Microenvironment-Modulated Metastatic CD133+/CXCR4+/EpCAM- Lung Cancer-Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis.
Bertolini G, D'Amico L, Moro M, Landoni E, Perego P, Miceli R, Gatti L, Andriani F, Wong D, Caserini R, Tortoreto M, Milione M, Ferracini R, Mariani L, Pastorino U, Roato I, Sozzi G, Roz L. Bertolini G, et al. Cancer Res. 2015 Sep 1;75(17):3636-49. doi: 10.1158/0008-5472.CAN-14-3781. Epub 2015 Jul 3. Cancer Res. 2015. PMID: 26141860
Conversion to stem-cell state in response to microenvironmental cues is regulated by balance between epithelial and mesenchymal features in lung cancer cells.
Andriani F, Bertolini G, Facchinetti F, Baldoli E, Moro M, Casalini P, Caserini R, Milione M, Leone G, Pelosi G, Pastorino U, Sozzi G, Roz L. Andriani F, et al. Among authors: bertolini g. Mol Oncol. 2016 Feb;10(2):253-71. doi: 10.1016/j.molonc.2015.10.002. Epub 2015 Oct 22. Mol Oncol. 2016. PMID: 26514616 Free PMC article.
426 results