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Visualizing ATP-dependent RNA translocation by the NS3 helicase from HCV.
Appleby TC, Anderson R, Fedorova O, Pyle AM, Wang R, Liu X, Brendza KM, Somoza JR. Appleby TC, et al. Among authors: wang r. J Mol Biol. 2011 Feb 4;405(5):1139-53. doi: 10.1016/j.jmb.2010.11.034. Epub 2010 Dec 9. J Mol Biol. 2011. PMID: 21145896 Free PMC article.
Cathepsin A is the major hydrolase catalyzing the intracellular hydrolysis of the antiretroviral nucleotide phosphonoamidate prodrugs GS-7340 and GS-9131.
Birkus G, Wang R, Liu X, Kutty N, MacArthur H, Cihlar T, Gibbs C, Swaminathan S, Lee W, McDermott M. Birkus G, et al. Among authors: wang r. Antimicrob Agents Chemother. 2007 Feb;51(2):543-50. doi: 10.1128/AAC.00968-06. Epub 2006 Dec 4. Antimicrob Agents Chemother. 2007. PMID: 17145787 Free PMC article.
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