Huang M - Search Results

1

Estimation of inhibitory quotient using a comparative equilibrium dialysis assay for prediction of viral response to hepatitis C virus inhibitors.

Mo H, Yang C, Wang K, Wang Y, Huang M, Murray B, Qi X, Sun SC, Deshpande M, Rhodes G, Miller MD. Mo H, et al. Among authors: huang m. J Viral Hepat. 2011 May;18(5):338-48. doi: 10.1111/j.1365-2893.2010.01314.x. J Viral Hepat. 2011. PMID: 20456634

2

Hepatitis C drug discovery: in vitro and in vivo systems and drugs in the pipeline.

Huang M, Deshpande M. Huang M, et al. Expert Rev Anti Infect Ther. 2004 Jun;2(3):375-88. doi: 10.1586/14787210.2.3.375. Expert Rev Anti Infect Ther. 2004. PMID: 15482203 Review.

3

Hepatitis C virus (HCV) NS5B nonnucleoside inhibitors specifically block single-stranded viral RNA synthesis catalyzed by HCV replication complexes in vitro.

Yang W, Sun Y, Phadke A, Deshpande M, Huang M. Yang W, et al. Among authors: huang m. Antimicrob Agents Chemother. 2007 Jan;51(1):338-42. doi: 10.1128/AAC.00498-06. Epub 2006 Nov 6. Antimicrob Agents Chemother. 2007. PMID: 17088480 Free PMC article.

4

ACH-806, an NS4A antagonist, inhibits hepatitis C virus replication by altering the composition of viral replication complexes.

Yang W, Sun Y, Hou X, Zhao Y, Fabrycki J, Chen D, Wang X, Agarwal A, Phadke A, Deshpande M, Huang M. Yang W, et al. Among authors: huang m. Antimicrob Agents Chemother. 2013 Jul;57(7):3168-77. doi: 10.1128/AAC.02630-12. Epub 2013 Apr 29. Antimicrob Agents Chemother. 2013. PMID: 23629709 Free PMC article.

5

Selection of replicon variants resistant to ACH-806, a novel hepatitis C virus inhibitor with no cross-resistance to NS3 protease and NS5B polymerase inhibitors.

Yang W, Zhao Y, Fabrycki J, Hou X, Nie X, Sanchez A, Phadke A, Deshpande M, Agarwal A, Huang M. Yang W, et al. Among authors: huang m. Antimicrob Agents Chemother. 2008 Jun;52(6):2043-52. doi: 10.1128/AAC.01548-07. Epub 2008 Apr 14. Antimicrob Agents Chemother. 2008. PMID: 18411324 Free PMC article.

6

Ferrocene-based inhibitors of hepatitis C virus replication that target NS5A with low picomolar in vitro antiviral activity.

Gadhachanda VR, Eastman KJ, Wang Q, Phadke AS, Patel D, Yang W, Marlor CW, Deshpande M, Huang M, Wiles JA. Gadhachanda VR, et al. Among authors: huang m. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3463-3471. doi: 10.1016/j.bmcl.2018.09.023. Epub 2018 Sep 18. Bioorg Med Chem Lett. 2018. PMID: 30290989

7

A highly sensitive and reproducible HCV RNA hybridization method valuable for antiviral drug discovery.

Zhao Y, Sanchez A, Nie X, Liu D, Hou X, Fabrycki J, Phadke A, Deshpande M, Huang M, Yang W. Zhao Y, et al. Among authors: huang m. J Virol Methods. 2008 Jul;151(1):154-7. doi: 10.1016/j.jviromet.2008.03.027. Epub 2008 May 8. J Virol Methods. 2008. PMID: 18466983

8

Discovery of novel dialkyl substituted thiophene inhibitors of HCV by in silico screening of the NS5B RdRp.

Louise-May S, Yang W, Nie X, Liu D, Deshpande MS, Phadke AS, Huang M, Agarwal A. Louise-May S, et al. Among authors: huang m. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3905-9. doi: 10.1016/j.bmcl.2007.04.103. Epub 2007 May 3. Bioorg Med Chem Lett. 2007. PMID: 17512198

9

Studies on hepatitis C virus resistance to inhibitors in replicon systems.

Zhao Y, Huang M. Zhao Y, et al. Among authors: huang m. Curr Protoc Pharmacol. 2010 Sep;Chapter 13:Unit 13B.2. doi: 10.1002/0471141755.ph13b02s50. Curr Protoc Pharmacol. 2010. PMID: 22294367

10

Evaluation of compound activity against hepatitis C virus in replicon systems.

Yang G, Huang M. Yang G, et al. Among authors: huang m. Curr Protoc Pharmacol. 2010 Sep;Chapter 13:Unit 13B.1. doi: 10.1002/0471141755.ph13b01s50. Curr Protoc Pharmacol. 2010. PMID: 22294366

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