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Complement drives Th17 cell differentiation and triggers autoimmune arthritis.
Hashimoto M, Hirota K, Yoshitomi H, Maeda S, Teradaira S, Akizuki S, Prieto-Martin P, Nomura T, Sakaguchi N, Köhl J, Heyman B, Takahashi M, Fujita T, Mimori T, Sakaguchi S. Hashimoto M, et al. J Exp Med. 2010 Jun 7;207(6):1135-43. doi: 10.1084/jem.20092301. Epub 2010 May 10. J Exp Med. 2010. PMID: 20457757 Free PMC article.
Arthritis and pneumonitis produced by the same T cell clones from mice with spontaneous autoimmune arthritis.
Wakasa-Morimoto C, Toyosaki-Maeda T, Matsutani T, Yoshida R, Nakamura-Kikuoka S, Maeda-Tanimura M, Yoshitomi H, Hirota K, Hashimoto M, Masaki H, Fujii Y, Sakata T, Tsuruta Y, Suzuki R, Sakaguchi N, Sakaguchi S. Wakasa-Morimoto C, et al. Among authors: hashimoto m. Int Immunol. 2008 Oct;20(10):1331-42. doi: 10.1093/intimm/dxn091. Epub 2008 Aug 18. Int Immunol. 2008. PMID: 18711120
Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis.
Ito Y, Usui T, Kobayashi S, Iguchi-Hashimoto M, Ito H, Yoshitomi H, Nakamura T, Shimizu M, Kawabata D, Yukawa N, Hashimoto M, Sakaguchi N, Sakaguchi S, Yoshifuji H, Nojima T, Ohmura K, Fujii T, Mimori T. Ito Y, et al. Among authors: hashimoto m. Arthritis Rheum. 2009 Aug;60(8):2294-303. doi: 10.1002/art.24687. Arthritis Rheum. 2009. PMID: 19644886 Free article.
4,705 results