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Suppression of aging in mice by the hormone Klotho.
Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P, McGuinness OP, Chikuda H, Yamaguchi M, Kawaguchi H, Shimomura I, Takayama Y, Herz J, Kahn CR, Rosenblatt KP, Kuro-o M. Kurosu H, et al. Science. 2005 Sep 16;309(5742):1829-33. doi: 10.1126/science.1112766. Epub 2005 Aug 25. Science. 2005. PMID: 16123266 Free PMC article.
Regulation of oxidative stress by the anti-aging hormone klotho.
Yamamoto M, Clark JD, Pastor JV, Gurnani P, Nandi A, Kurosu H, Miyoshi M, Ogawa Y, Castrillon DH, Rosenblatt KP, Kuro-o M. Yamamoto M, et al. J Biol Chem. 2005 Nov 11;280(45):38029-34. doi: 10.1074/jbc.M509039200. Epub 2005 Sep 26. J Biol Chem. 2005. PMID: 16186101 Free PMC article.
Regulation of fibroblast growth factor-23 signaling by klotho.
Kurosu H, Ogawa Y, Miyoshi M, Yamamoto M, Nandi A, Rosenblatt KP, Baum MG, Schiavi S, Hu MC, Moe OW, Kuro-o M. Kurosu H, et al. J Biol Chem. 2006 Mar 10;281(10):6120-3. doi: 10.1074/jbc.C500457200. Epub 2006 Jan 25. J Biol Chem. 2006. PMID: 16436388 Free PMC article.
Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members.
Goetz R, Beenken A, Ibrahimi OA, Kalinina J, Olsen SK, Eliseenkova AV, Xu C, Neubert TA, Zhang F, Linhardt RJ, Yu X, White KE, Inagaki T, Kliewer SA, Yamamoto M, Kurosu H, Ogawa Y, Kuro-o M, Lanske B, Razzaque MS, Mohammadi M. Goetz R, et al. Mol Cell Biol. 2007 May;27(9):3417-28. doi: 10.1128/MCB.02249-06. Epub 2007 Mar 5. Mol Cell Biol. 2007. PMID: 17339340 Free PMC article.
BetaKlotho is required for metabolic activity of fibroblast growth factor 21.
Ogawa Y, Kurosu H, Yamamoto M, Nandi A, Rosenblatt KP, Goetz R, Eliseenkova AV, Mohammadi M, Kuro-o M. Ogawa Y, et al. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7432-7. doi: 10.1073/pnas.0701600104. Epub 2007 Apr 23. Proc Natl Acad Sci U S A. 2007. PMID: 17452648 Free PMC article.
295 results