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The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response.
Blanc M, Hsieh WY, Robertson KA, Kropp KA, Forster T, Shui G, Lacaze P, Watterson S, Griffiths SJ, Spann NJ, Meljon A, Talbot S, Krishnan K, Covey DF, Wenk MR, Craigon M, Ruzsics Z, Haas J, Angulo A, Griffiths WJ, Glass CK, Wang Y, Ghazal P. Blanc M, et al. Immunity. 2013 Jan 24;38(1):106-18. doi: 10.1016/j.immuni.2012.11.004. Epub 2012 Dec 27. Immunity. 2013. PMID: 23273843 Free PMC article.
Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis.
Blanc M, Hsieh WY, Robertson KA, Watterson S, Shui G, Lacaze P, Khondoker M, Dickinson P, Sing G, Rodríguez-Martín S, Phelan P, Forster T, Strobl B, Müller M, Riemersma R, Osborne T, Wenk MR, Angulo A, Ghazal P. Blanc M, et al. PLoS Biol. 2011 Mar;9(3):e1000598. doi: 10.1371/journal.pbio.1000598. Epub 2011 Mar 8. PLoS Biol. 2011. PMID: 21408089 Free PMC article.
Reversible inhibition of murine cytomegalovirus replication by gamma interferon (IFN-γ) in primary macrophages involves a primed type I IFN-signaling subnetwork for full establishment of an immediate-early antiviral state.
Kropp KA, Robertson KA, Sing G, Rodriguez-Martin S, Blanc M, Lacaze P, Hassim MF, Khondoker MR, Busche A, Dickinson P, Forster T, Strobl B, Mueller M, Jonjic S, Angulo A, Ghazal P. Kropp KA, et al. J Virol. 2011 Oct;85(19):10286-99. doi: 10.1128/JVI.00373-11. Epub 2011 Jul 20. J Virol. 2011. PMID: 21775459 Free PMC article.
Whole blood gene expression profiling of neonates with confirmed bacterial sepsis.
Dickinson P, Smith CL, Forster T, Craigon M, Ross AJ, Khondoker MR, Ivens A, Lynn DJ, Orme J, Jackson A, Lacaze P, Flanagan KL, Stenson BJ, Ghazal P. Dickinson P, et al. Genom Data. 2014 Nov 15;3:41-8. doi: 10.1016/j.gdata.2014.11.003. eCollection 2015 Mar. Genom Data. 2014. PMID: 26484146 Free PMC article.
85 results