Tyrrell L - Search Results

1

Alternative splicing may contribute to time-dependent manifestation of inherited erythromelalgia.

Choi JS, Cheng X, Foster E, Leffler A, Tyrrell L, Te Morsche RH, Eastman EM, Jansen HJ, Huehne K, Nau C, Dib-Hajj SD, Drenth JP, Waxman SG. Choi JS, et al. Among authors: tyrrell l. Brain. 2010 Jun;133(Pt 6):1823-35. doi: 10.1093/brain/awq114. Epub 2010 May 16. Brain. 2010. PMID: 20478850

2

Structure of the sodium channel gene SCN11A: evidence for intron-to-exon conversion model and implications for gene evolution.

Dib-Hajj SD, Tyrrell L, Waxman SG. Dib-Hajj SD, et al. Among authors: tyrrell l. Mol Neurobiol. 2002 Oct-Dec;26(2-3):235-50. doi: 10.1385/MN:26:2-3:235. Mol Neurobiol. 2002. PMID: 12428758 Review.

3

Functional role of the C-terminus of voltage-gated sodium channel Na(v)1.8.

Choi JS, Tyrrell L, Waxman SG, Dib-Hajj SD. Choi JS, et al. Among authors: tyrrell l. FEBS Lett. 2004 Aug 13;572(1-3):256-60. doi: 10.1016/j.febslet.2004.07.047. FEBS Lett. 2004. PMID: 15304358 Free article.

4

Differential modulation of sodium channel Na(v)1.6 by two members of the fibroblast growth factor homologous factor 2 subfamily.

Rush AM, Wittmack EK, Tyrrell L, Black JA, Dib-Hajj SD, Waxman SG. Rush AM, et al. Among authors: tyrrell l. Eur J Neurosci. 2006 May;23(10):2551-62. doi: 10.1111/j.1460-9568.2006.04789.x. Eur J Neurosci. 2006. PMID: 16817858

5

Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating.

Lampert A, Dib-Hajj SD, Tyrrell L, Waxman SG. Lampert A, et al. Among authors: tyrrell l. J Biol Chem. 2006 Nov 24;281(47):36029-35. doi: 10.1074/jbc.M607637200. Epub 2006 Sep 28. J Biol Chem. 2006. PMID: 17008310 Free article.

6

Na(V)1.7 mutant A863P in erythromelalgia: effects of altered activation and steady-state inactivation on excitability of nociceptive dorsal root ganglion neurons.

Harty TP, Dib-Hajj SD, Tyrrell L, Blackman R, Hisama FM, Rose JB, Waxman SG. Harty TP, et al. Among authors: tyrrell l. J Neurosci. 2006 Nov 29;26(48):12566-75. doi: 10.1523/JNEUROSCI.3424-06.2006. J Neurosci. 2006. PMID: 17135418 Free PMC article.

7

Mutation I136V alters electrophysiological properties of the Na(v)1.7 channel in a family with onset of erythromelalgia in the second decade.

Cheng X, Dib-Hajj SD, Tyrrell L, Waxman SG. Cheng X, et al. Among authors: tyrrell l. Mol Pain. 2008 Jan 2;4:1. doi: 10.1186/1744-8069-4-1. Mol Pain. 2008. PMID: 18171466 Free PMC article.

8

Phosphorylation of sodium channel Na(v)1.8 by p38 mitogen-activated protein kinase increases current density in dorsal root ganglion neurons.

Hudmon A, Choi JS, Tyrrell L, Black JA, Rush AM, Waxman SG, Dib-Hajj SD. Hudmon A, et al. Among authors: tyrrell l. J Neurosci. 2008 Mar 19;28(12):3190-201. doi: 10.1523/JNEUROSCI.4403-07.2008. J Neurosci. 2008. PMID: 18354022 Free PMC article.

9

A pore-blocking hydrophobic motif at the cytoplasmic aperture of the closed-state Nav1.7 channel is disrupted by the erythromelalgia-associated F1449V mutation.

Lampert A, O'Reilly AO, Dib-Hajj SD, Tyrrell L, Wallace BA, Waxman SG. Lampert A, et al. Among authors: tyrrell l. J Biol Chem. 2008 Aug 29;283(35):24118-27. doi: 10.1074/jbc.M802900200. Epub 2008 Jun 12. J Biol Chem. 2008. PMID: 18550534 Free PMC article.

10

Mexiletine-responsive erythromelalgia due to a new Na(v)1.7 mutation showing use-dependent current fall-off.

Choi JS, Zhang L, Dib-Hajj SD, Han C, Tyrrell L, Lin Z, Wang X, Yang Y, Waxman SG. Choi JS, et al. Among authors: tyrrell l. Exp Neurol. 2009 Apr;216(2):383-9. doi: 10.1016/j.expneurol.2008.12.012. Epub 2008 Dec 31. Exp Neurol. 2009. PMID: 19162012

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