Lustgarten J - Search Results

1

Blockade of CCL1 inhibits T regulatory cell suppressive function enhancing tumor immunity without affecting T effector responses.

Hoelzinger DB, Smith SE, Mirza N, Dominguez AL, Manrique SZ, Lustgarten J. Hoelzinger DB, et al. Among authors: lustgarten j. J Immunol. 2010 Jun 15;184(12):6833-42. doi: 10.4049/jimmunol.0904084. Epub 2010 May 7. J Immunol. 2010. PMID: 20483762

2

High accumulation of T regulatory cells prevents the activation of immune responses in aged animals.

Sharma S, Dominguez AL, Lustgarten J. Sharma S, et al. Among authors: lustgarten j. J Immunol. 2006 Dec 15;177(12):8348-55. doi: 10.4049/jimmunol.177.12.8348. J Immunol. 2006. PMID: 17142731

3

CpG-ODN but not other TLR-ligands restore the antitumor responses in old mice: the implications for vaccinations in the aged.

Sharma S, Dominguez AL, Hoelzinger DB, Lustgarten J. Sharma S, et al. Among authors: lustgarten j. Cancer Immunol Immunother. 2008 Apr;57(4):549-61. doi: 10.1007/s00262-007-0393-1. Epub 2007 Sep 8. Cancer Immunol Immunother. 2008. PMID: 17828396 Free PMC article.

4

Implications of aging and self-tolerance on the generation of immune and antitumor immune responses.

Dominguez AL, Lustgarten J. Dominguez AL, et al. Among authors: lustgarten j. Cancer Res. 2008 Jul 1;68(13):5423-31. doi: 10.1158/0008-5472.CAN-07-6436. Cancer Res. 2008. PMID: 18593945

5

Systemic targeting of CpG-ODN to the tumor microenvironment with anti-neu-CpG hybrid molecule and T regulatory cell depletion induces memory responses in BALB-neuT tolerant mice.

Sharma S, Dominguez AL, Manrique SZ, Cavallo F, Sakaguchi S, Lustgarten J. Sharma S, et al. Among authors: lustgarten j. Cancer Res. 2008 Sep 15;68(18):7530-40. doi: 10.1158/0008-5472.CAN-08-1635. Cancer Res. 2008. PMID: 18794141 Free PMC article.

6

Targeting the tumor microenvironment with anti-neu/anti-CD40 conjugated nanoparticles for the induction of antitumor immune responses.

Dominguez AL, Lustgarten J. Dominguez AL, et al. Among authors: lustgarten j. Vaccine. 2010 Feb 3;28(5):1383-90. doi: 10.1016/j.vaccine.2009.10.153. Epub 2009 Nov 18. Vaccine. 2010. PMID: 19931385 Free PMC article.

7

B7-H1 expression on old CD8+ T cells negatively regulates the activation of immune responses in aged animals.

Mirza N, Duque MA, Dominguez AL, Schrum AG, Dong H, Lustgarten J. Mirza N, et al. Among authors: lustgarten j. J Immunol. 2010 May 15;184(10):5466-5474. doi: 10.4049/jimmunol.0903561. Epub 2010 Apr 7. J Immunol. 2010. PMID: 20375308 Free PMC article.

8

Foxp3-positive macrophages display immunosuppressive properties and promote tumor growth.

Manrique SZ, Correa MA, Hoelzinger DB, Dominguez AL, Mirza N, Lin HH, Stein-Streilein J, Gordon S, Lustgarten J. Manrique SZ, et al. Among authors: lustgarten j. J Exp Med. 2011 Jul 4;208(7):1485-99. doi: 10.1084/jem.20100730. Epub 2011 Jun 13. J Exp Med. 2011. Retraction in: J Exp Med. 2011 Nov 21;208(12):2561. doi: 10.1084/jem.2010073020812r PMID: 21670203 Free PMC article. Retracted.

9

Comparative kinetic analyses of gene profiles of naïve CD4+ and CD8+ T cells from young and old animals reveal novel age-related alterations.

Mirza N, Pollock K, Hoelzinger DB, Dominguez AL, Lustgarten J. Mirza N, et al. Among authors: lustgarten j. Aging Cell. 2011 Oct;10(5):853-67. doi: 10.1111/j.1474-9726.2011.00730.x. Epub 2011 Aug 7. Aging Cell. 2011. PMID: 21711441 Free PMC article.

10

Signals through 4-1BB inhibit T regulatory cells by blocking IL-9 production enhancing antitumor responses.

Smith SE, Hoelzinger DB, Dominguez AL, Van Snick J, Lustgarten J. Smith SE, et al. Among authors: lustgarten j. Cancer Immunol Immunother. 2011 Dec;60(12):1775-87. doi: 10.1007/s00262-011-1075-6. Epub 2011 Jul 26. Cancer Immunol Immunother. 2011. PMID: 21789593 Free PMC article.

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