Prabhakar BS - Search Results

1

Akt-phosphorylated mitogen-activated kinase-activating death domain protein (MADD) inhibits TRAIL-induced apoptosis by blocking Fas-associated death domain (FADD) association with death receptor 4.

Li P, Jayarama S, Ganesh L, Mordi D, Carr R, Kanteti P, Hay N, Prabhakar BS. Li P, et al. Among authors: prabhakar bs. J Biol Chem. 2010 Jul 16;285(29):22713-22. doi: 10.1074/jbc.M110.105692. Epub 2010 May 18. J Biol Chem. 2010. PMID: 20484047 Free PMC article.

2

Contrasting effects of IG20 and its splice isoforms, MADD and DENN-SV, on tumor necrosis factor alpha-induced apoptosis and activation of caspase-8 and -3.

Al-Zoubi AM, Efimova EV, Kaithamana S, Martinez O, El-Idrissi Mel-A, Dogan RE, Prabhakar BS. Al-Zoubi AM, et al. Among authors: prabhakar bs. J Biol Chem. 2001 Dec 14;276(50):47202-11. doi: 10.1074/jbc.M104835200. Epub 2001 Sep 27. J Biol Chem. 2001. PMID: 11577081 Free article.

3

Apoptosis and autoimmune disorders.

Prasad KV, Prabhakar BS. Prasad KV, et al. Among authors: prabhakar bs. Autoimmunity. 2003 Sep-Nov;36(6-7):323-30. doi: 10.1080/08916930310001604207. Autoimmunity. 2003. PMID: 14669939 Free article. Review.

4

IG20, a MADD splice variant, increases cell susceptibility to gamma-irradiation and induces soluble mediators that suppress tumor cell growth.

Efimova E, Martinez O, Lokshin A, Arima T, Prabhakar BS. Efimova E, et al. Among authors: prabhakar bs. Cancer Res. 2003 Dec 15;63(24):8768-76. Cancer Res. 2003. PMID: 14695193

5

IG20, in contrast to DENN-SV, (MADD splice variants) suppresses tumor cell survival, and enhances their susceptibility to apoptosis and cancer drugs.

Efimova EV, Al-Zoubi AM, Martinez O, Kaithamana S, Lu S, Arima T, Prabhakar BS. Efimova EV, et al. Among authors: prabhakar bs. Oncogene. 2004 Feb 5;23(5):1076-87. doi: 10.1038/sj.onc.1207210. Oncogene. 2004. PMID: 14716293

6

IG20 (MADD splice variant-5), a proapoptotic protein, interacts with DR4/DR5 and enhances TRAIL-induced apoptosis by increasing recruitment of FADD and caspase-8 to the DISC.

Ramaswamy M, Efimova EV, Martinez O, Mulherkar NU, Singh SP, Prabhakar BS. Ramaswamy M, et al. Among authors: prabhakar bs. Oncogene. 2004 Aug 12;23(36):6083-94. doi: 10.1038/sj.onc.1207804. Oncogene. 2004. PMID: 15208670

7

MADD/DENN splice variant of the IG20 gene is necessary and sufficient for cancer cell survival.

Mulherkar N, Ramaswamy M, Mordi DC, Prabhakar BS. Mulherkar N, et al. Among authors: prabhakar bs. Oncogene. 2006 Oct 12;25(47):6252-61. doi: 10.1038/sj.onc.1209650. Epub 2006 May 8. Oncogene. 2006. PMID: 16682944

8

Diversity in the complementarity-determining region 3 (CDR3) of antibodies from mice with evolving anti-thyroid-stimulating hormone receptor antibody responses.

Martinez O, Gangi E, Mordi D, Gupta S, Dorevitch S, Lefranc MP, Prabhakar BS. Martinez O, et al. Among authors: prabhakar bs. Endocrinology. 2007 Feb;148(2):752-61. doi: 10.1210/en.2006-1096. Epub 2006 Oct 26. Endocrinology. 2007. PMID: 17068139

9

MADD/DENN splice variant of the IG20 gene is a negative regulator of caspase-8 activation. Knockdown enhances TRAIL-induced apoptosis of cancer cells.

Mulherkar N, Prasad KV, Prabhakar BS. Mulherkar N, et al. Among authors: prabhakar bs. J Biol Chem. 2007 Apr 20;282(16):11715-21. doi: 10.1074/jbc.M701085200. Epub 2007 Feb 21. J Biol Chem. 2007. PMID: 17314102 Free article.

10

Down-regulation of catalase and oxidative modification of protein kinase CK2 lead to the failure of apoptosis repressor with caspase recruitment domain to inhibit cardiomyocyte hypertrophy.

Murtaza I, Wang HX, Feng X, Alenina N, Bader M, Prabhakar BS, Li PF. Murtaza I, et al. Among authors: prabhakar bs. J Biol Chem. 2008 Mar 7;283(10):5996-6004. doi: 10.1074/jbc.M706466200. Epub 2008 Jan 1. J Biol Chem. 2008. PMID: 18171680 Free article.

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