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Early bactericidal activity and pharmacokinetics of PA-824 in smear-positive tuberculosis patients.
Diacon AH, Dawson R, Hanekom M, Narunsky K, Maritz SJ, Venter A, Donald PR, van Niekerk C, Whitney K, Rouse DJ, Laurenzi MW, Ginsberg AM, Spigelman MK. Diacon AH, et al. Among authors: dawson r. Antimicrob Agents Chemother. 2010 Aug;54(8):3402-7. doi: 10.1128/AAC.01354-09. Epub 2010 May 24. Antimicrob Agents Chemother. 2010. PMID: 20498324 Free PMC article. Clinical Trial.
Why Do We Use 600 mg of Rifampicin in Tuberculosis Treatment?
van Ingen J, Aarnoutse RE, Donald PR, Diacon AH, Dawson R, Plemper van Balen G, Gillespie SH, Boeree MJ. van Ingen J, et al. Among authors: dawson r. Clin Infect Dis. 2011 May;52(9):e194-9. doi: 10.1093/cid/cir184. Clin Infect Dis. 2011. PMID: 21467012 Review.
Direct comparison of Xpert MTB/RIF assay with liquid and solid mycobacterial culture for quantification of early bactericidal activity.
Kayigire XA, Friedrich SO, Venter A, Dawson R, Gillespie SH, Boeree MJ, Heinrich N, Hoelscher M, Diacon AH; Pan African Consortium for the Evaluation of Anti-tuberculosis Antibiotics. Kayigire XA, et al. Among authors: dawson r. J Clin Microbiol. 2013 Jun;51(6):1894-8. doi: 10.1128/JCM.03290-12. Epub 2013 Apr 17. J Clin Microbiol. 2013. PMID: 23596237 Free PMC article.
Protein binding of rifampicin is not saturated when using high-dose rifampicin.
Litjens CHC, Aarnoutse RE, van Ewijk-Beneken Kolmer EWJ, Svensson EM, Colbers A, Burger DM, Boeree MJ, Te Brake LHM; PanACEA-MAMS-TB-01 Team. Litjens CHC, et al. J Antimicrob Chemother. 2019 Apr 1;74(4):986-990. doi: 10.1093/jac/dky527. J Antimicrob Chemother. 2019. PMID: 30597025 Clinical Trial.
PET/CT guided tuberculosis treatment shortening: a randomized trial.
Malherbe ST, Chen RY, Yu X, Smith B, Liu X, Gao J, Diacon AH, Dawson R, Tameris M, Zhu H, Qu Y, Jin H, Pan S, Dodd LE, Wang J, Goldfeder LC, Cai Y, Arora K, Vincent J, Narunsky K, Serole K, Goliath RT, Da Costa L, Taliep A, Aziz S, Daroowala R, Thienemann F, Mukasa S, Court R, Sossen B, Ahlers P, Mendelsohn SC, White L, Gouel A, Lau CY, Hassan S, Liang L, Duan H, Moghaddam GK, Paripati P, Lahouar S, Harris M, Wollenberg K, Jeffrey B, Tartakovsky M, Rosenthal A, Duvenhage M, Armstrong DT, Song T, Winter J, Gao Q, Via LE, Wilkinson RJ, Walzl G, Barry CE 3rd. Malherbe ST, et al. Among authors: dawson r. medRxiv [Preprint]. 2024 Oct 4:2024.10.03.24314723. doi: 10.1101/2024.10.03.24314723. medRxiv. 2024. PMID: 39802795 Free PMC article. Preprint.
Safety, bactericidal activity, and pharmacokinetics of the antituberculosis drug candidate BTZ-043 in South Africa (PanACEA-BTZ-043-02): an open-label, dose-expansion, randomised, controlled, phase 1b/2a trial.
Heinrich N, de Jager V, Dreisbach J, Gross-Demel P, Schultz S, Gerbach S, Kloss F, Dawson R, Narunsky K, Matt L, Wildner L, McHugh TD, Fuhr U, Aldana BH, Mouhdad C, Brake LT, Boeree MJ, Aarnoutse RE, Svensson EM, Gong X, P J Phillips P, Diacon AH, Hoelscher M; PanACEA-TB consortium. Heinrich N, et al. Among authors: dawson r. Lancet Microbe. 2024 Dec 26:100952. doi: 10.1016/j.lanmic.2024.07.015. Online ahead of print. Lancet Microbe. 2024. PMID: 39793592 Free article.
1,201 results