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Page 1
The suppressor of cytokine signalling 2 (SOCS2) is a key repressor of insulin secretion.
Lebrun P, Cognard E, Gontard P, Bellon-Paul R, Filloux C, Berthault MF, Magnan C, Ruberte J, Luppo M, Pujol A, Pachera N, Herchuelz A, Bosch F, Van Obberghen E. Lebrun P, et al. Among authors: pachera n. Diabetologia. 2010 Sep;53(9):1935-46. doi: 10.1007/s00125-010-1786-9. Epub 2010 May 25. Diabetologia. 2010. PMID: 20499047 Free article.
Heterozygous inactivation of the Na/Ca exchanger increases glucose-induced insulin release, β-cell proliferation, and mass.
Nguidjoe E, Sokolow S, Bigabwa S, Pachera N, D'Amico E, Allagnat F, Vanderwinden JM, Sener A, Manto M, Depreter M, Mast J, Joanny G, Montanya E, Rahier J, Cardozo AK, Eizirik DL, Schurmans S, Herchuelz A. Nguidjoe E, et al. Among authors: pachera n. Diabetes. 2011 Aug;60(8):2076-85. doi: 10.2337/db10-0924. Epub 2011 Jun 9. Diabetes. 2011. PMID: 21659499 Free PMC article.
Plasma membrane Ca2+-ATPase overexpression depletes both mitochondrial and endoplasmic reticulum Ca2+ stores and triggers apoptosis in insulin-secreting BRIN-BD11 cells.
Jiang L, Allagnat F, Nguidjoe E, Kamagate A, Pachera N, Vanderwinden JM, Brini M, Carafoli E, Eizirik DL, Cardozo AK, Herchuelz A. Jiang L, et al. Among authors: pachera n. J Biol Chem. 2010 Oct 1;285(40):30634-43. doi: 10.1074/jbc.M110.116681. Epub 2010 Jul 26. J Biol Chem. 2010. PMID: 20660595 Free PMC article.
DNAJC3 deficiency induces β-cell mitochondrial apoptosis and causes syndromic young-onset diabetes.
Lytrivi M, Senée V, Salpea P, Fantuzzi F, Philippi A, Abdulkarim B, Sawatani T, Marín-Cañas S, Pachera N, Degavre A, Singh P, Derbois C, Lechner D, Ladrière L, Igoillo-Esteve M, Cosentino C, Marselli L, Deleuze JF, Marchetti P, Eizirik DL, Nicolino M, Chaussenot A, Julier C, Cnop M. Lytrivi M, et al. Among authors: pachera n. Eur J Endocrinol. 2021 Mar;184(3):455-468. doi: 10.1530/EJE-20-0636. Eur J Endocrinol. 2021. PMID: 33486469
15 results