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Activated d16HER2 homodimers and SRC kinase mediate optimal efficacy for trastuzumab.
Castagnoli L, Iezzi M, Ghedini GC, Ciravolo V, Marzano G, Lamolinara A, Zappasodi R, Gasparini P, Campiglio M, Amici A, Chiodoni C, Palladini A, Lollini PL, Triulzi T, Menard S, Nanni P, Tagliabue E, Pupa SM. Castagnoli L, et al. Among authors: ghedini gc. Cancer Res. 2014 Nov 1;74(21):6248-59. doi: 10.1158/0008-5472.CAN-14-0983. Epub 2014 Aug 27. Cancer Res. 2014. PMID: 25164009
Pathobiological implications of the d16HER2 splice variant for stemness and aggressiveness of HER2-positive breast cancer.
Castagnoli L, Ghedini GC, Koschorke A, Triulzi T, Dugo M, Gasparini P, Casalini P, Palladini A, Iezzi M, Lamolinara A, Lollini PL, Nanni P, Chiodoni C, Tagliabue E, Pupa SM. Castagnoli L, et al. Among authors: ghedini gc. Oncogene. 2017 Mar 23;36(12):1721-1732. doi: 10.1038/onc.2016.338. Epub 2016 Sep 19. Oncogene. 2017. PMID: 27641338 Free PMC article.
Serological identification of HSP105 as a novel non-Hodgkin lymphoma therapeutic target.
Zappasodi R, Bongarzone I, Ghedini GC, Castagnoli L, Cabras AD, Messina A, Tortoreto M, Tripodo C, Magni M, Carlo-Stella C, Gianni AM, Pupa SM, Di Nicola M. Zappasodi R, et al. Among authors: ghedini gc. Blood. 2011 Oct 20;118(16):4421-30. doi: 10.1182/blood-2011-06-364570. Epub 2011 Aug 22. Blood. 2011. PMID: 21860023 Free article.
FGF Trapping Inhibits Multiple Myeloma Growth through c-Myc Degradation-Induced Mitochondrial Oxidative Stress.
Ronca R, Ghedini GC, Maccarinelli F, Sacco A, Locatelli SL, Foglio E, Taranto S, Grillo E, Matarazzo S, Castelli R, Paganini G, Desantis V, Cattane N, Cattaneo A, Mor M, Carlo-Stella C, Belotti A, Roccaro AM, Presta M, Giacomini A. Ronca R, et al. Among authors: ghedini gc. Cancer Res. 2020 Jun 1;80(11):2340-2354. doi: 10.1158/0008-5472.CAN-19-2714. Epub 2020 Feb 24. Cancer Res. 2020. PMID: 32094301 Free article.
Future applications of FGF/FGFR inhibitors in cancer.
Ghedini GC, Ronca R, Presta M, Giacomini A. Ghedini GC, et al. Expert Rev Anticancer Ther. 2018 Sep;18(9):861-872. doi: 10.1080/14737140.2018.1491795. Epub 2018 Jul 2. Expert Rev Anticancer Ther. 2018. PMID: 29936878 Review.
Modeling Acquired Resistance to the Second-Generation Androgen Receptor Antagonist Enzalutamide in the TRAMP Model of Prostate Cancer.
Cerasuolo M, Maccarinelli F, Coltrini D, Mahmoud AM, Marolda V, Ghedini GC, Rezzola S, Giacomini A, Triggiani L, Kostrzewa M, Verde R, Paris D, Melck D, Presta M, Ligresti A, Ronca R. Cerasuolo M, et al. Among authors: ghedini gc. Cancer Res. 2020 Apr 1;80(7):1564-1577. doi: 10.1158/0008-5472.CAN-18-3637. Epub 2020 Feb 6. Cancer Res. 2020. PMID: 32029552
Long pentraxin 3: A novel multifaceted player in cancer.
Giacomini A, Ghedini GC, Presta M, Ronca R. Giacomini A, et al. Among authors: ghedini gc. Biochim Biophys Acta Rev Cancer. 2018 Jan;1869(1):53-63. doi: 10.1016/j.bbcan.2017.11.004. Epub 2017 Nov 23. Biochim Biophys Acta Rev Cancer. 2018. PMID: 29175552 Review.
13 results